It has been estimated that ~18-36% of cell lines utilized in biomedical research are contaminated and/or are completely misidentified1. Consequently, verification of human cell line identity is of critical significance since the validity of data obtained depends on authenticity of the cell line. TRIP offers Short Tandem Repeat (STR) analysis to verify the authenticity of human cell lines. Some funding organizations, along with major publishers, such as those affiliated with the American Association for Cancer Research (AACR), have established requirements for cell line authentication prior to publication.
When you submit samples for authentication you will receive a report indicating STR and Amelogenin genotypes for all loci. The report includes an interpretative comment regarding any indication of possible sample contamination (2% sensitivity) and evaluation (identification or authentication of cell line identity) relative to a publication, repository database or a baseline specimen.
For questions or inquiries, please contact Rebecca Baus at email@example.com or firstname.lastname@example.org.
For pricing please see our TRIP Fee Schedule. To request STR services, go to our iLab webpage.