In Review
*Limkar AR, Ricke EA., Vrba SM, Fabry Z, Lee MT, McVary KT, Ricke WA. Targeting fibrosis in the treatment of lower urinary tract dysfunction. Journal of Pathology. 2025. In Review.
2025 in preprint
*Golfinos-Owens AE, Lozar T, Khatri P, Hu R, Harari PM, Lambert PF, Fitzpatrick MB, Dinh HQ. Integrated single-cell and spatial analysis identifies context-dependent myeloid-T cell interactions in head and neck cancer immune checkpoint blockade response. bioRxiv [Preprint]. 2025 Mar 28:2025.03.24.644582. doi: 10.1101/2025.03.24.644582. PMID: 40196610; PMCID: PMC11974738
*Sophia M. Vrba, Collin Laaker, Ajinkya R. Limkar, Martin Hsu, William A. Ricke, Tyler K. Ulland, Mariana Pehar, Matyas Sandor, Zsuzsanna Fabry. Amyloid-beta deposition and reduced drainage at the cribriform plate lymphatics in APP/PS1 mouse model of Alzheimer’s Disease. bioRxiv 2025.05.15.654007; doi: https://doi.org/10.1101/2025.05.15.654007
* Minton DM, Ailiani AR, Focht MDK, Kersh ME, Li A, Elliehausen CJ, Sonsalla MM, Lamming DW, Marolf AJ, Santangelo KS, Salmon AB, Konopka AR. Inhibition of mTORC1 by rapamycin results in feedback activation of AktS473 and aggravates hallmarks of osteoarthritis in female mice and non-human primates. bioRxiv [Preprint]. 2025 Mar 6:2024.05.14.594256. doi: 10.1101/2024.05.14.594256. PMID: 38798488; PMCID: PMC11118493.
* Landowski M, Hagimori R, Gogoi P, Bhute VJ, Ikeda S, Takimoto T, Ikeda A. Mitochondrial fusion controls the development of specialized mitochondrial structure and metabolism in rod photoreceptor cells. bioRxiv [Preprint]. 2025 May 26:2025.05.21.655403. doi: 10.1101/2025.05.21.655403. PMID: 40501800; PMCID: PMC12154637.
2025
Hayes M, Wang W, Fraga de Andrade I, Lambert PF, Sugden B. Kaposi sarcoma-associated herpesvirus cooperates with Epstein-Barr virus to co-transform a small set of human B cells oncogenically. PLoS Pathog. 2025 Jun 23;21(6):e1013281. doi: 10.1371/journal.ppat.1013281. PMID: 40549805; PMCID: PMC12204619.
Schmidt JK, Wilson RL, Davenport BN, Hacker TA, Fitz C, Simmons HA, Schotzko ML, Golos TG, Jones HN. Nanoparticle-mediated delivery of placental gene therapy via uterine artery catheterization in a pregnant rhesus macaque. Placenta. 2025 Jun 13;166:103-108. doi: 10.1016/j.placenta.2024.09.013. Epub 2024 Sep 20. PMID: 39362807; PMCID: PMC11947900.
Crossman BE, Harmon RL, Iida M, Adams JM, Lin CY, Glitchev CE, Juang TD, Kerr SC, Alexandridis RA, Hyun M, Yang DT, Kang I, Salgia R, Wheeler DL. Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer. Front Oncol. 2025 May 5;15:1579214. doi: 10.3389/fonc.2025.1579214. PMID: 40391157; PMCID: PMC12086072.
Krabbe NP, Mitzey AM, Bhattacharya S, Razo ER, Zeng X, Bekiares N, Moy A, Kamholz A, Karl JA, Daggett G, VanSleet G, Morgan T, Capuano SV, Simmons HA, Basu P, Weiler AM, O’Connor DH, Friedrich TC, Golos TG, Mohr EL. Clade IIb Mpox virus (MPXV) vertical transmission and fetal demise in a pregnant rhesus macaque model. PLoS One. 2025 Apr 1;20(4):e0320671. doi: 10.1371/journal.pone.0320671. PMID: 40168332; PMCID: PMC11960918.
Polaki US, Gilpin TE, Patil AT, Chiu E, Baker R, Liu P, Pavletich TS, Seifi M, Mañán-Mejías PM, Morrissey J, Port J, Welch Schwartz R, Ong IM, El-Rayes D, Khalifa MA, Hui P, Horner VL, Virumbrales-Muñoz M, Erickson BK, Barroilhet L, McGregor SM, Bresnick EH, Matson DR. Loss of GATA2 promotes invasion and predicts cancer recurrence and survival in uterine serous carcinoma. JCI Insight. 2025 Apr 1;10(9):e187073. doi: 10.1172/jci.insight.187073. PMID: 40168074; PMCID: PMC12128953.
Kostecki KL, Harmon RL, Iida M, Harris MA, Crossman BE, Bruce JY, Salgia R, Wheeler DL. Axl Regulation of NK Cell Activity Creates an Immunosuppressive Tumor Immune Microenvironment in Head and Neck Cancer. Cancers (Basel). 2025 Mar 15;17(6):994. doi: 10.3390/cancers17060994. PMID: 40149328; PMCID: PMC11940164.
Zhang X, Lan R, Liu Y, Pillarisetty VG, Li D, Zhao CL, Sarkar SA, Liu W, Hanna I, Gupta M, Hajdu C, Melamed J, Shusterman M, Widmer J, Allendorf J, Liu YZ. Complement activation in tumor microenvironment after neoadjuvant therapy and its impact on pancreatic cancer outcomes. NPJ Precis Oncol. 2025 Mar 3;9(1):58. doi: 10.1038/s41698-025-00848-2. PMID: 40032924; PMCID: PMC11876354.
Ramírez-Flores CJ, Hryckowian ND, Gale AN, Babatunde KA, Lares M, Beebe DJ, Kerr SC, Knoll LJ. Modeling Toxoplasma gondii-gut early interactions using a human microphysiological system. PLoS Negl Trop Dis. 2025 Feb 4;19(2):e0012855. doi: 10.1371/journal.pntd.0012855. Epub ahead of print. PMID: 39903779.
Downs TM, Bailey HH, Lozar T, Schmitz NS, Green H, Scarlett CO, Havighurst TC, Twaroski K, DeShong K, Wollmer B, Bivalacqua TJ, Saltzstein DR, Shore N, Kim K, Huang W, Ricke WA, Barroilhet L, House M, Parnes HL, Messing E. Phase II Clinical Chemoprevention Trial of Weekly Erlotinib before Bladder Cancer Surgery. Cancer Prev Res (Phila). 2025 Jan 6;18(1):31-39. doi: 10.1158/1940-6207.CAPR-24-0194. PMID: 39187984; PMCID: PMC11703677.
Lin EC, Davis MP, Lee MS, Ma G, Xu W, Chang YI, Li WJ. Advancing immunomodulatory functions in mesenchymal stem/stromal cells through targeting the GATA6-mediated pathway. Cytotherapy. 2025 Jan;27(1):85-97. doi: 10.1016/j.jcyt.2024.08.001. Epub 2024 Aug 8. PMID: 39207345; PMCID: PMC11668624.
Oikawa K, Eaton JS, Kiland JA, Torné O, Mathu V, Nickells RW, McLellan GJ. Intravitreal AAV2 gene delivery to feline retinal ganglion cells. Vision Res. 2025 Jan;226:108519. doi: 10.1016/j.visres.2024.108519. Epub 2024 Nov 16. PMID: 39549467; PMCID: PMC11658774.
Mohanty C, Singh CK, Daccache JA, Damsky W, Kendziorski C, Yan D, Prasad A, Zhang D, Keenan T, Drolet B, Ahmad N, Shields BE. Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics. J Invest Dermatol. 2025 Jan;145(1):109-121. doi: 10.1016/j.jid.2024.04.024. Epub 2024 Jun 4. PMID: 38844128.
2024
Keske A, Polaki US, Matson DR. Immunohistochemical Analysis of GATA2 Expression in Endometrium and its Relationship with Hormone Receptor Expression in Benign and Premalignant Endometrial Disorders. Reprod Sci. 2024 Dec;31(12):3880-3891. doi: 10.1007/s43032-024-01730-5. Epub 2024 Oct 23. PMID: 39443360; PMCID: PMC11611599.
Neuman SD, Thakur RS, Gratz SJ, O’Connor-Giles KM, Bashirullah A. Neurodegenerative and neurodevelopmental roles for bulk lipid transporters VPS13Aand BLTP2in movement disorders. bioRxiv [Preprint]. 2024 Dec 30:2024.12.30.630795. doi: 10.1101/2024.12.30.630795. PMID: 39803515; PMCID: PMC11722402.
Minne RL, Luo NY, Mork CM, Wopat MR, Esbona K, Javeri S, Nickel KP, Hernandez R, LeBeau AM, Kimple RJ, Baschnagel AM. Evaluation of a Novel MET-Targeting Camelid-Derived Antibody in Head and Neck Cancer. Mol Pharm. 2024 Dec 2;21(12):6376-6384. doi: 10.1021/acs.molpharmaceut.4c00938. Epub 2024 Nov 8. PMID: 39513517.
Sharma K, Esbona K, Eickhoff JC, Lloyd RV, Hu R. Long non-coding RNA MALAT 1 and PHOX2B expression in olfactory neuroblastomas and sympathetic neuroblastomas. Ann Diagn Pathol. 2024 Dec;73:152355. doi: 10.1016/j.anndiagpath.2024.152355. Epub 2024 Jun 11. PMID: 38878689.
Lettman MM, Mendina CA, Burkard E, Alvin JR, Zhu Y, Coon JJ, Audhya A. Cell type-specific gene therapy confers protection against motor neuron disease caused by a TFG variant. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2410996121. doi: 10.1073/pnas.2410996121. Epub 2024 Nov 11. PMID: 39527745; PMCID: PMC11588061.
Wilson RL, Kropp Schmidt J, Davenport BN, Ren E, Keding LT, Shaw SA, Schotzko ML, Antony KM, Simmons HA, Golos TG, Jones HN. Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates. bioRxiv [Preprint]. 2023 Dec 14:2023.06.16.545278. doi: 10.1101/2023.06.16.545278. Update in: Mol Hum Reprod. 2024 Nov 14;30(11):gaae038. doi: 10.1093/molehr/gaae038. PMID: 38168281; PMCID: PMC10760006.
Crossman BE, Harmon RL, Kostecki KL, McDaniel NK, Iida M, Corday LW, Glitchev CE, Crow MT, Harris MA, Lin CY, Adams JM, Longhurst CA, Nickel KP, Ong IM, Alexandridis RA, Yu M, Yang DT, Hu R, Morris ZS, Hartig GK, Glazer TA, Ramisetty S, Kulkarni P, Salgia R, Kimple RJ, Bruce JY, Harari PM, Wheeler DL. From Bench to Bedside: A Team’s Approach to Multidisciplinary Strategies to Combat Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma. J Clin Med. 2024 Oct 10;13(20):6036. doi: 10.3390/jcm13206036. PMID: 39457986; PMCID: PMC11508784.
Tannenbaum AP, Lozar T, Lu C, Schumacher M, Golfinos A, Dinh HQ, Taylor N, Kimple RJ, Yang D, Harari PM, Lambert PF, Lloyd RV, Hu R. Uncommon and Challenging Phenotypes of High-Risk Human Papillomavirus-Associated Head and Neck Carcinomas Revealed by High-Throughput Studies. Head Neck Pathol. 2024 Oct 22;18(1):112. doi: 10.1007/s12105-024-01707-5. PMID:39436498; PMCID: PMC11496466.
Sharma S, Feng L, Boonpattrawong N, Kapur A, Barroilhet L, Patankar MS, Ericksen SS. Data mining of PubChem bioassay records reveals diverse OXPHOS inhibitory chemotypes as potential therapeutic agents against ovarian cancer. J Cheminform. 2024 Oct 7;16(1):112. doi: 10.1186/s13321-024-00906-0. PMID: 39375760; PMCID: PMC11460086.
Copeland SE, Snow SM, Wan J, Matkowskyj KA, Halberg RB, Weaver BA. MAD1 upregulation sensitizes to inflammation-mediated tumor formation. PLoS Genet. 2024 Oct 7;20(10):e1011437. doi: 10.1371/journal.pgen.1011437. PMID: 39374311; PMCID: PMC11486420.
Damodharan S, Shireman JM, Xie E, Distler E, Kendziorski C, Dey M. Transcriptomic and proteomic spatial profiling of pediatric and adult diffuse midline glioma H3 K27-Altered. Sci Rep. 2024 Sep 30;14(1):22668. doi: 10.1038/s41598-024-73199-w. PMID: 39349581; PMCID: PMC11443003.
Turner DGP, De Lange WJ, Zhu Y, Coe CL, Simcox J, Ge Y, Kamp TJ, Ralphe JC, Glukhov AV. Neutral sphingomyelinase regulates mechanotransduction in human engineered cardiac tissues and mouse hearts. J Physiol. 2024 Sep;602(18):4387-4407. doi: 10.1113/JP284807. Epub 2023 Oct 27. PMID: 37889115; PMCID: PMC11052922.
Cosper PF, Paracha M, Jones KM, Hrycyniak L, Henderson L, Bryan A, Eyzaguirre D, McCunn E, Boulanger E, Wan J, Nickel KP, Horner V, Hu R, Harari PM, Kimple RJ, Weaver BA. Chromosomal instability increases radiation sensitivity. bioRxiv [Preprint]. 2024 Sep 19:2024.09.13.612942. doi: 10.1101/2024.09.13.612942. PMID: 39345631; PMCID: PMC11429890.
Jagodinsky JC, Vera JM, Jin WJ, Shea AG, Clark PA, Sriramaneni RN, Havighurst TC, Chakravarthy I, Allawi RH, Kim K, Harari PM, Sondel PM, Newton MA, Crittenden MR, Gough MJ, Miller JR, Ong IM, Morris ZS. Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade. Sci Transl Med. 2024 Sep 18;16(765):eadk0642. doi: 10.1126/scitranslmed.adk0642. Epub 2024 Sep 18. PMID: 39292804; PMCID: PMC11522033.
Adi W, Perez BER, Liu Y, Runkle S, Eliceiri KW, Yesilkoy F. Machine learning assisted mid-infrared spectrochemical fibrillar collagen imaging in clinical tissues. bioRxiv [Preprint]. 2024 May 26:2024.05.22.595393. doi: 10.1101/2024.05.22.595393. Update in: J Biomed Opt. 2024 Sep;29(9):093511. doi: 10.1117/1.JBO.29.9.093511. PMID: 38826188; PMCID: PMC11142197.
Nennig K, Murthy S, Maloney S, Shaw TM, Sharobim M, Matkovic E, Fadiran S, Larsen M, Ramuta MD, Kim AS, Teijaro JR, Grove J, Stremlau M, Sharma H, Trivedi S, Blum MJ, O’Connor DH, Hyde JL, Stapleton JT, Kapoor A, Bailey AL. Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse. PLoS Pathog. 2024 Aug 28;20(8):e1012436. doi: 10.1371/journal.ppat.1012436. PMID: 39196893; PMCID: PMC11355568.
Manuel RS, Rundquist A, Ambrogi M, Scharpf BR, Peterson NT, Sandhu JK, Chandrashekar S, Ridlon M, Crawford LK, Keil-Stietz KP, Peterson RE, Vezina CM. The aryl hydrocarbon receptor agonist ITE reduces inflammation and urinary dysfunction in a mouse model of autoimmune prostatitis. Am J Clin Exp Urol. 2024 Aug 25;12(4):149-161. doi: 10.62347/PEGK4888. PMID: 39308590; PMCID: PMC11411176.
Zheng, C.; Allen, K.O.; Liu, T.; Solodin, N.M.; Meyer, M.B.; Salem, K.; Tsourkas, P.K.; McIlwain, S.J.; Vera, J.M.; Cromwell, E.R.; et al. Elevated GRHL2 Imparts Plasticity in ER-Positive Breast Cancer Cells. Cancers 2024, 16, 2906. Aug 21, 2024.
Jagodinsky JC, Vera JM, Jin WJ, Shea AG, Clark PA, Sriramaneni RN, Havighurst TC, Chakravarthy I, Allawi RH, Kim K, Harari PM, Sondel PM, Newton MA, Crittenden MR, Gough MJ, Miller JR, Ong IM, Morris ZS. Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade. Sci Transl Med. 2024 Sep 18;16(765):eadk0642. doi: 10.1126/scitranslmed.adk0642. Epub 2024 Sep 18. PMID: 39292804; PMCID: PMC11522033.
Tucker JB, Carlsen CL, Scribano CM, Pattaswamy SM, Burkard ME, Weaver BA. CENP-E Inhibition Induces Chromosomal Instability and Synergizes with Diverse Microtubule-Targeting Agents in Breast Cancer. Cancer Res. 2024 Aug 15;84(16):2674-2689. doi: 10.1158/0008-5472.CAN-23-3332. PMID: 38832939; PMCID: PMC11326998.
Abi-Saab T, Lozar T, Chen Y, Tannenbaum AP, Geye H, Yu M, Weisman P, Harari PM, Kimple RJ, Lambert PF, Lloyd RV, Hu R. Morphologic Spectrum of HPV-associated Sinonasal Carcinomas. Head Neck Pathol. 2024 Aug 5;18(1):67. doi: 10.1007/s12105-024-01670-1. PMID: 39101976; PMCID: PMC11300749.
Albertini,M.R.; Zuleger,C.L.; Ranheim, E.A.; Shiyanbola, O.; Sondel, P.M.; Morris, Z.S.; Eickhoff, J.; Newton, M.; Ong, I.M.; Schwartz, R.W.; Hayim, R.; Kurzman, I.D.; Michelle, T.; Vail, D.M. Administration of intratumoral GD2-directed interleukin-2 immunocytokine and local radiation therapy to activate rejection of spontaneous canine melanoma. Melanoma Research 2024 Aug 1;34(4):307-318. PMID: 38768442. link: https://journals.lww.com/melanomaresearch/abstract/2024/08000/administration_of_intratumoral_gd2_directed.3.aspx
Popovics P, Silver SV, Uchtmann KS, Arendt LM, Vezina CM, Ricke WA. CCR2+monocytes/macrophages drive steroid hormone imbalance-related prostatic fibrosis. Sci Rep. 2024 Jul 8;14(1):15736. doi: 10.1038/s41598-024-65574-4. PMID: 38977751; PMCID: PMC11231243.
Skibba ME, Brasier AR. NF-κB/RelA signaling in secretoglobin progenitors mediates plasticity and MMP-induced barrier disruption in house dust mite-induced allergic asthma. Am J Physiol Lung Cell Mol Physiol. 2024 Jul 1;327(1):L86-L101. doi: 10.1152/ajplung.00066.2024. Epub 2024 May 7. PMID: 38713619; PMCID: PMC11380976.
Zhang X, Lan R, Liu Y, Pillarisetty VG, Li D, Zhao CL, Sarkar SA, Liu W, Hanna I, Gupta M, Hajdu C, Melamed J, Shusterman M, Widmer J, Allendorf J, Liu YZ. Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma. Res Sq [Preprint]. 2024 May 13:rs.3.rs-4104258. doi: 10.21203/rs.3.rs-4104258/v1. PMID: 38798691; PMCID: PMC11118688.
Garcia EM, Lenz JD, Schaub RE, Hackett KT, Salgado-Pabón W, Dillard JP. IL-17C is a driver of damaging inflammation during Neisseria gonorrhoeae infection of human Fallopian tube. Nat Commun. 2024 May 4;15(1):3756. doi: 10.1038/s41467-024-48141-3. PMID: 38704381; PMCID: PMC11069574.
Iida M, Crossman BE, Kostecki KL, Glitchev CE, Kranjac CA, Crow MT, Adams JM, Liu P, Ong I, Yang DT, Kang I, Salgia R, Wheeler DL. MerTK Drives Proliferation and Metastatic Potential in Triple-Negative Breast Cancer. Int J Mol Sci. 2024 May 8;25(10):5109. doi: 10.3390/ijms25105109. PMID: 38791148; PMCID: PMC11121248.
Heaton AR, Burkard NJ, Sondel PM, Skala MC. Quantifying in vivocollagen reorganization during immunotherapy in murine melanoma with second harmonic generation imaging. Biophotonics Discov. 2024 May;1(1):015004. doi: 10.1117/1.bios.1.1.015004. Epub 2024 May 20. PMID: 39011049; PMCID: PMC11247620.
Micek HM, Yang N, Dutta M, Rosenstock L, Ma Y, Hielsberg C, McCord M, Notbohm J, McGregor S, Kreeger PK. The role of Piezo1 mechanotransduction in high-grade serous ovarian cancer: Insights from an in vitro model of collective detachment. Sci Adv. 2024 Apr 26;10(17):eadl4463. doi: 10.1126/sciadv.adl4463. Epub 2024 Apr 26. PMID: 38669327; PMCID: PMC11051664.
Hamilton HL, Kinscherf NA, Balmer G, Bresque M, Salamat SM, Vargas MR, Pehar M. FABP7 drives an inflammatory response in human astrocytes and is upregulated in Alzheimer’s disease. Geroscience. 2024 Apr;46(2):1607-1625. doi: 10.1007/s11357-023-00916-0. Epub 2023 Sep 9. PMID: 37688656; PMCID: PMC10828232.
Shireman JM, White Q, Ni Z, Mohanty C, Cai Y, Zhao L, Agrawal N, Gonugunta N, Wang X, Mccarthy L, Kasulabada V, Pattnaik A, Ahmed AU, Miller J, Kulwin C, Cohen-Gadol A, Payner T, Lin CT, Savage JJ, Lane B, Shiue K, Kamer A, Shah M, Iyer G, Watson G, Kendziorski C, Dey M. Genomic analysis of human brain metastases treated with stereotactic radiosurgery reveals unique signature based on treatment failure. iScience. 2024 Mar 27;27(4):109601. doi: 10.1016/j.isci.2024.109601. PMID: 38623341; PMCID: PMC11016778.
Shen AL, Moran SM, Glover EN, Lin BC, Carney PR, Bradfield CA. Familial isolated pituitary adenoma is independent of Ahrgenotype in a novel mouse model of disease. Heliyon. 2024 Mar 26;10(7):e28231. doi: 10.1016/j.heliyon.2024.e28231. PMID: 38590848; PMCID: PMC10999881.
Faralli JA, Filla MS, Yang YF, Sun YY, Johns K, Keller KE, Peters DM. Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15. PLoS One. 2024 Feb 23;19(2):e0298802. doi: 10.1371/journal.pone.0298802. PMID: 38394161; PMCID: PMC10889904.
Wang CW, Weaver SD, Boonpattrawong N, Schuster-Little N, Patankar M, Whelan RJ. A Revised Molecular Model of Ovarian Cancer Biomarker CA125 (MUC16) Enabled by Long-read Sequencing. Cancer Res Commun. 2024 Jan 31;4(1):253-263. doi: 10.1158/2767-9764.CRC-23-0327. PMID: 38197671; PMCID: PMC10829539.
Shapiro DD, Lozar T, Cheng L, Xie E, Laklouk I, Lee MH, Huang W, Jarrard DF, Allen GO, Hu R, Kinoshita T, Esbona K, Lambert PF, Capitini CM, Kendziorski C, Abel EJ. Non-Metastatic Clear Cell Renal Cell Carcinoma Immune Cell Infiltration Heterogeneity and Prognostic Ability in Patients Following Surgery. Cancers (Basel). 2024 Jan 23;16(3):478. doi: 10.3390/cancers16030478. PMID: 38339231; PMCID: PMC10854750.
Chhabra G, Singh CK, Ndiaye MA, Su S, Shirley CA, Ahmad N. Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanoma. NPJ Precis Oncol. 2024 Jan 6;8(1):6. doi: 10.1038/s41698-023-00493-7. PMID: 38184733; PMCID: PMC10771520.
Harris L, Mitzey A, Keding L, Shaw S, Ren E, Al-Mugotir M,Renshall L, Beards F, Simmons H, Basu P, Schotzko M, Chen R,Liu R-Y, Wieben O, Golos T, Schmidt J, Targeted delivery of liposomes to the uterine artery of pregnant rhesus macaques, Placenta, Volume 154, 2024, Page e79, ISSN 0143-4004, https://doi.org/10.1016/j.placenta.2024.07.287.(https://www.sciencedirect.com/science/article/pii/S0143400424005824)
2023
Jin WJ, Jagodinsky JC, Vera JM, Clark PA, Zuleger CL, Erbe AK, Ong IM, Le T, Tetreault K, Berg T, Rakhmilevich AL, Kim K, Newton MA, Albertini MR, Sondel PM, Morris ZS. NK cells propagate T cell immunity following in situ tumor vaccination. Cell Rep. 2023 Dec 26;42(12):113556. doi: 10.1016/j.celrep.2023.113556. Epub 2023 Dec 13. PMID: 38096050; PMCID: PMC10843551.
Schneider AJ, Serrell EC, Grimes M, Wang S, Bushman W. Histologic inflammation and collagen content are not positively correlated in human BPH. Prostate. 2023 Dec;83(16):1529-1536. doi: 10.1002/pros.24611. Epub 2023 Aug 21. PMID: 37602498.
Chang HY, Huynh M, Roopra A, Callander NS, Miyamoto S. HAPLN1 matrikine: a bone marrow homing factor linked to poor outcomes in patients with MM. Blood Adv. 2023 Nov 28;7(22):6859-6872. doi: 10.1182/bloodadvances.2023010139. PMID: 37647592; PMCID: PMC10685165
Su S, Ndiaye MA, Guzmán-Pérez G, Baus RM, Huang W, Patankar MS, Ahmad N. Potential Tumor Suppressor Role of Polo-like Kinase 5 in Cancer. Cancers (Basel). 2023 Nov 17;15(22):5457. doi: 10.3390/cancers15225457. PMID: 38001717; PMCID: PMC10669931.
Sauter MM, Noel H, Brandt CR. The RLR intrinsic antiviral system is expressed in neural retina and restricts lentiviral transduction of human Mueller cells. Exp Eye Res. 2023 Nov;236:109647. doi: 10.1016/j.exer.2023.109647. Epub 2023 Sep 7. PMID: 37689341; PMCID: PMC10834037.
Patil AT, Bennett DD, Xu J, Weisman P, Matson DR. Spatial transcriptomics of a giant pilomatricoma. J Cutan Pathol. 2023 Nov;50(11):963-970. doi: 10.1111/cup.14524. Epub 2023 Aug 30. PMID: 37649312; PMCID: PMC10591970.
Zhou AS, Tucker JB, Scribano CM, Lynch AR, Carlsen CL, Pop-Vicas ST, Pattaswamy SM, Burkard ME, Weaver BA. Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles. PLoS Biol. 2023 Oct 26;21(10):e3002339. doi: 10.1371/journal.pbio.3002339. PMID: 37883329; PMCID: PMC10602348.
Lozar T, Laklouk I, Golfinos AE, Gavrielatou N, Xu J, Flynn C, Keske A, Yu M, Bruce JY, Wang W, Grasic Kuhar C, Bailey HH, Harari PM, Dinh HQ, Rimm DL, Hu R, Lambert PF, Fitzpatrick MB. Stress Keratin 17 Is a Predictive Biomarker Inversely Associated with Response to Immune Check-Point Blockade in Head and Neck Squamous Cell Carcinomas and Beyond. Cancers (Basel). 2023 Oct 9;15(19):4905. doi: 10.3390/cancers15194905. PMID: 37835599; PMCID: PMC10571921.
Lozar T, Keske A, Dube Mandishora RS, Yu Q, Bailey A, Xu J, Tommasino M, McGregor SM, Lambert PF, Gheit T, Fitzpatrick MB. Betapapillomavirusesin p16-Negative Vulvar Intraepithelial Lesions Associated with Squamous Cell Carcinoma. Viruses. 2023 Sep 19;15(9):1950. doi: 10.3390/v15091950. PMID: 37766356; PMCID: PMC10537070.
Koenig MR, Mitzey AM, Zeng X, Reyes L, Simmons HA, Morgan TK, Bohm EK, Pritchard JC, Schmidt JA, Ren E, Leyva Jaimes FB, Winston E, Basu P, Weiler AM, Friedrich TC, Aliota MT, Mohr EL, Golos TG. Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus macaque (Macaca mulatta) model. PLoS Pathog. 2023 Aug 7;19(8):e1011274. doi: 10.1371/journal.ppat.1011274. PMID: 37549143; PMCID: PMC10434957.
Samimi K, Contreras Guzman E, Wu M, Carlson L, Feltovich H, Hall TJ, Myers KM, Oyen ML, Skala MC. Optical coherence tomography of human fetal membrane sub-layers during loading. Biomed Opt Express. 2023 May 25;14(6):2969-2985. doi: 10.1364/BOE.489691. PMID: 37342693; PMCID: PMC10278609.
Koenig MR, Mitzey AM, Morgan TK, Zeng X, Simmons HA, Mejia A, Leyva Jaimes F, Keding LT, Crooks CM, Weiler AM, Bohm EK, Aliota MT, Friedrich TC, Mohr EL, Golos TG. Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus. PLoS One. 2023 May 4;18(5):e0284964. doi: 10.1371/journal.pone.0284964. PMID: 37141276; PMCID: PMC10159132.
Cosper PF, Hrycyniak LCF, Paracha M, Lee DL, Wan J, Jones K, Bice SA, Nickel K, Mallick S, Taylor AM, Kimple RJ, Lambert PF, Weaver BA. HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2216700120. doi: 10.1073/pnas.2216700120. Epub 2023 Mar 29. PMID: 36989302; PMCID: PMC10083562.
Samimi K, Contreras Guzman E, Wu M, Carlson L, Feltovich H, Hall TJ, Myers KM, Oyen ML, Skala MC. Optical coherence tomography of human fetal membrane sub-layers during loading. Biomed Opt Express. 2023 May 25;14(6):2969-2985. doi: 10.1364/BOE.489691. PMID: 37342693; PMCID: PMC10278609.
Weisman P, Yu Q, Xu J. Clinicopathological characteristics of the SOX10+ subset of HER2+ breast cancer. Ann Diagn Pathol. 2023 Apr;63:152087. doi: 10.1016/j.anndiagpath.2022.152087. Epub 2022 Dec 23. PMID: 36669230.
Heaton AR, Rehani PR, Hoefges A, Lopez AF, Erbe AK, Sondel PM, Skala MC. Single cell metabolic imaging of tumor and immune cells in vivo in melanoma bearing mice. Front Oncol. 2023 Mar 20;13:1110503. doi: 10.3389/fonc.2023.1110503. PMID: 37020875; PMCID: PMC10067577.
Cordes BA, Bilger A, Kraus RJ, Ward-Shaw ET, Labott MR, Lee S, Lambert PF, Mertz JE. Drugs That Mimic Hypoxia Selectively Target EBV-Positive Gastric Cancer Cells. Cancers (Basel). 2023 Mar 19;15(6):1846. doi: 10.3390/cancers15061846. PMID: 36980731; PMCID: PMC10046841
Landowski M, Grindel S, Hao Y, Ikeda S, Bowes Rickman C, Ikeda A. A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration. J Vis Exp. 2023 Mar 10;(193):10.3791/64927. doi: 10.3791/64927. PMID: 36971449; PMCID: PMC10311451.
Fonseca MAS, Haro M, Wright KN, Lin X, Abbasi F, Sun J, Hernandez L, Orr NL, Hong J, Choi-Kuaea Y, Maluf HM, Balzer BL, Fishburn A, Hickey R, Cass I, Goodridge HS, Truong M, Wang Y, Pisarska MD, Dinh HQ, El-Naggar A, Huntsman DG, Anglesio MS, Goodman MT, Medeiros F, Siedhoff M, Lawrenson K. Single-cell transcriptomic analysis of endometriosis. Nat Genet. 2023 Feb;55(2):255-267. doi: 10.1038/s41588-022-01254-1. Epub 2023 Jan 9. PMID: 36624343; PMCID: PMC10950360.
Singh CK, Mintie CA, Ndiaye MA, Chhabra G, Roy S, Sullivan R, Longley BJ, Schieke SM, Ahmad N. Protective effects of dietary grape against atopic dermatitis-like skin lesions in NC/NgaTndCrlj mice. Front Immunol. 2023 Jan 19;13:1051472. doi: 10.3389/fimmu.2022.1051472. PMID: 36741360; PMCID: PMC9893861.
Tucker JB, Bonema SC, García-Varela R, Denu RA, Hu Y, McGregor SM, Burkard ME, Weaver BA. Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer. Cancer Res Commun. 2023 Jan 12;3(1):54-65. doi: 10.1158/2767-9764.CRC-22-0302. PMID: 36968230; PMCID: PMC10035514.
Mikheil D, Prabhakar K, Ng TL, Teertam S, Longley BJ, Newton MA, Setaluri V. Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice. Cancers (Basel). 2023 Jan 14;15(2):519. doi: 10.3390/cancers15020519. PMID: 36672468; PMCID: PMC9857214.
Landowski M, Bhute VJ, Grindel S, Haugstad Z, Gyening YK, Tytanic M, Brush RS, Moyer LJ, Nelson DW, Davis CR, Yen CE, Ikeda S, Agbaga MP, Ikeda A. Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism. Commun Biol. 2023 Jan 4;6(1):8. doi: 10.1038/s42003-022-04404-7. PMID: 36599953; PMCID: PMC9813353.
Lee MS, Lin EC, Sivapatham A, Leiferman EM, Jiao H, Lu Y, Nemke BW, Leiferman M, Markel MD, Li WJ. Autologous iPSC- and MSC-derived chondrocyte implants for cartilage repair in a miniature pig model. Stem Cell Res Ther. 2025 Feb 23;16(1):86. doi: 10.1186/s13287-025-04215-7. PMID: 39988676; PMCID: PMC11849328.
2022
Zhao SG, Sperger JM, Schehr JL, McKay RR, Emamekhoo H, Singh A, Schultz ZD, Bade RM, Stahlfeld CN, Gilsdorf CS, Hernandez CI, Wolfe SK, Mayberry RD, Krause HM, Bootsma M, Helzer KT, Rydzewski N, Bakhtiar H, Shi Y, Blitzer G, Kyriakopoulos CE, Kosoff D, Wei XX, Floberg J, Sethakorn N, Sharifi M, Harari PM, Huang W, Beltran H, Choueiri TK, Scher HI, Rathkopf DE, Halabi S, Armstrong AJ, Beebe DJ, Yu M, Sundling KE, Taplin ME, Lang JM. A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer. J Clin Invest. 2022 Nov 1;132(21):e161858. doi: 10.1172/JCI161858. PMID: 36317634; PMCID: PMC9621140
Lee MH, Sung K, Beebe D, Huang W, Shapiro D, Miyamoto S, Abel EJ. The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells. Oncogenesis. 2022 Oct 25;11(1):65. doi: 10.1038/s41389-022-00440-4. PMID: 36284084; PMCID: PMC9596416.
Lechner SA, Welsch JM, Pahapill NK, Kaldenberg TAR, Regenbaum A, Kelm-Nelson CA. Predictors of prodromal Parkinson’s disease in young adult Pink1-/-rats. Front Behav Neurosci. 2022 Sep 12;16:867958. doi: 10.3389/fnbeh.2022.867958. PMID: 36172466; PMCID: PMC9510667.
Toulany M, Iida M, Lettau K, Coan JP, Rebholz S, Khozooei S, Harari PM, Wheeler DL. Targeting HER3-dependent activation of nuclear AKT improves radiotherapy of non-small cell lung cancer. Radiother Oncol. 2022 Sep;174:92-100. doi: 10.1016/j.radonc.2022.07.008. Epub 2022 Jul 15. PMID: 35839938; PMCID: PMC10083767.
Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment. Cell Rep. 2022 Aug 16;40(7):111201. doi: 10.1016/j.celrep.2022.111201. PMID: 35977482; PMCID: PMC9402878.
Liu Y, Al-Adra DP, Lan R, Jung G, Li H, Yeh MM, Liu YZ. RNA sequencing analysis of hepatocellular carcinoma identified oxidative phosphorylation as a major pathologic feature. Hepatol Commun. 2022 Aug;6(8):2170-2181. doi: 10.1002/hep4.1945. Epub 2022 Mar 28. PMID: 35344307; PMCID: PMC9315135.
Matson DR, Accola MA, Henderson L, Shao X, Frater-Rubsam L, Horner VL, Rehrauer WM, Weisman P, Xu J. A “Null” Pattern of p16 Immunostaining in Endometrial Serous Carcinoma: An Under-recognized and Important Aberrant Staining Pattern. Int J Gynecol Pathol. 2022 Jul 1;41(4):378-388. doi: 10.1097/PGP.0000000000000817. Epub 2021 Aug 11. PMID: 34380970; PMCID: PMC8831662.
Wang W, Lozar T, Golfinos AE, Lee D, Gronski E, Ward-Shaw E, Hayes M, Bruce JY, Kimple RJ, Hu R, Harari PM, Xu J, Keske A, Sondel PM, Fitzpatrick MB, Dinh HQ, Lambert PF. Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade. Clin Cancer Res. 2022 Jul 1;28(13):2953-2968. doi: 10.1158/1078-0432.CCR-21-3039. PMID: 35621713; PMCID: PMC9250640.
Jiao H, Lee MS, Sivapatham A, Leiferman EM, Li WJ. Epigenetic regulation of BAF60A determines efficiency of miniature swine iPSC generation. Sci Rep. 2022 May 31;12(1):9039. doi: 10.1038/s41598-022-12919-6. Erratum in: Sci Rep. 2022 Jun 17;12(1):10193. doi: 10.1038/s41598-022-14878-4. PMID: 35641537; PMCID: PMC9156668.
Ni Z, Prasad A, Chen S, Halberg RB, Arkin LM, Drolet BA, Newton MA, Kendziorski C. SpotClean adjusts for spot swapping in spatial transcriptomics data. Nat Commun. 2022 May 27;13(1):2971. doi: 10.1038/s41467-022-30587-y. PMID: 35624112; PMCID: PMC9142522.
Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, Johannsen EC, Dinh HQ, Kenney SC. Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells. PLoS Pathog. 2022 Apr 26;18(4):e1010453. doi: 10.1371/journal.ppat.1010453. PMID: 35472072; PMCID: PMC9041801.
Iida M, McDaniel NK, Kostecki KL, Welke NB, Kranjac CA, Liu P, Longhurst C, Bruce JY, Hong S, Salgia R, Wheeler DL. AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer. BMC Cancer. 2022 Apr 23;22(1):447. doi: 10.1186/s12885-022-09511-6. PMID: 35461210; PMCID: PMC9035247.
Chhabra G, Singh CK, Guzmán-Pérez G, Ndiaye MA, Iczkowski KA, Ahmad N. Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in BrafV600E/PtenNULL Mice. J Invest Dermatol. 2022 Apr;142(4):1145-1157.e7. doi: 10.1016/j.jid.2021.08.434. Epub 2021 Sep 29. PMID: 34597611; PMCID: PMC9199498.
Cagaanan A, Stelter B, Vu N, Rhode EN, Stewart T, Hui P, Buza N, Al-Niaimi A, Flynn C, Weisman PS, McGregor SM. HER2 Expression in Endometrial Cancers Diagnosed as Clear Cell Carcinoma. Int J Gynecol Pathol. 2022 Mar 1;41(2):132-141. doi: 10.1097/PGP.0000000000000783. PMID: 33782344.
Bernau K, Skibba M, Leet JP, Furey S, Gehl C, Li Y, Zhou J, Sandbo N, Brasier AR. Selective Inhibition of Bromodomain-Containing Protein 4 Reduces Myofibroblast Transdifferentiation and Pulmonary Fibrosis. Front Mol Med. 2022;2:842558. doi: 10.3389/fmmed.2022.842558. Epub 2022 Mar 15. PMID: 35782526; PMCID: PMC9245900.
Renner C, Gomez C, Visetsouk MR, Taha I, Khan A, McGregor SM, Weisman P, Naba A, Masters KS, Kreeger PK. Multi-modal Profiling of the Extracellular Matrix of Human Fallopian Tubes and Serous Tubal Intraepithelial Carcinomas. J Histochem Cytochem. 2022 Feb;70(2):151-168. doi: 10.1369/00221554211061359. Epub 2021 Dec 5. PMID: 34866441; PMCID: PMC8777377.
Snow SM, Matkowskyj KA, Maresh M, Clipson L, Vo TN, Johnson KA, Deming DA, Newton MA, Grady WM, Pickhardt PJ, Halberg RB. Validation of genetic classifiers derived from mouse and human tumors to identify molecular subtypes of colorectal cancer. Hum Pathol. 2022 Jan;119:1-14. doi: 10.1016/j.humpath.2021.10.002. Epub 2021 Oct 14. PMID: 34655611; PMCID: PMC9936405.
Landowski M, Bhute VJ, Takimoto T, Grindel S, Shahi PK, Pattnaik BR, Ikeda S, Ikeda A. A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups. Sci Rep. 2022 Jan 14;12(1):756. doi: 10.1038/s41598-021-04644-3. PMID: 35031662; PMCID: PMC8760256.
2021
Li H, Hardin H, Zaeem M, Huang W, Hu R, Lloyd RV. LncRNA expression and SDHB mutations in pheochromocytomas and paragangliomas. Ann Diagn Pathol. 2021 Dec;55:151801. doi: 10.1016/j.anndiagpath.2021.151801. Epub 2021 Jul 31. PMID: 34461576.
Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O’Regan R, McGregor SM, Fowler AM, Chappell RJ, Bugni TS, Burkard ME, Weaver BA. Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel. Sci Transl Med. 2021 Sep 8;13(610):eabd4811. doi: 10.1126/scitranslmed.abd4811. Epub 2021 Sep 8. PMID: 34516829; PMCID: PMC8612166.
Magee K, Marsh IR, Turek MM, Grudzinski J, Aluicio-Sarduy E, Engle JW, Kurzman ID, Zuleger CL, Oseid EA, Jaskowiak C, Albertini MR, Esbona K, Bednarz B, Sondel PM, Weichert JP, Morris ZS, Hernandez R, Vail DM. Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting. PLoS One. 2021 Aug 12;16(8):e0255798. doi: 10.1371/journal.pone.0255798. eCollection 2021. PMID: 34383787
Filon M, Gawdzik J, Truong A, Allen G, Huang W, Khemees T, Machhi R, Lewis P, Yang B, Denu J, Jarrard D. Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype. Br J Cancer. 2021 Jul;125(2):247-254. doi: 10.1038/s41416-021-01398-7. Epub 2021 May 11. PMID: 33976366; PMCID: PMC8292389.
Heaster TM, Heaton AR, Sondel PM, Skala MC. Intravital Metabolic Autofluorescence Imaging Captures Macrophage Heterogeneity Across Normal and Cancerous Tissue. Front Bioeng Biotechnol. 2021 Apr 20;9:644648. doi: 10.3389/fbioe.2021.644648. PMID: 33959597; PMCID: PMC8093439.
Sauter MM, Brandt CR. Knockdown of TRIM5α or TRIM11 increases lentiviral vector transduction efficiency of human Muller cells. Exp Eye Res. 2021 Mar;204:108436. doi: 10.1016/j.exer.2021.108436. Epub 2021 Jan 10. PMID: 33440192; PMCID: PMC7946771.
Su S, Chhabra G, Ndiaye MA, Singh CK, Ye T, Huang W, Dewey CN, Setaluri V, Ahmad N. PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways. Mol Cancer Ther. 2021 Jan;20(1):161-172. doi: 10.1158/1535-7163.MCT-20-0654. Epub 2020 Nov 11. PMID: 33177155; PMCID: PMC7790869.
2020
Shiyanbola O, Hardin H, Hu R, Eickhoff JC, Lloyd RV. Long Noncoding RNA Expression in Adrenal Cortical Neoplasms. Endocr Pathol. 2020 Dec;31(4):385-391. doi: 10.1007/s12022-020-09642-1. Epub 2020 Jul 28. PMID: 32725507.
Yang B, Damodaran S, Khemees TA, Filon MJ, Schultz A, Gawdzik J, Etheridge T, Malin D, Richards KA, Cryns VL, Jarrard DF. Synthetic Lethal Metabolic Targeting of Androgen-Deprived Prostate Cancer Cells with Metformin. Mol Cancer Ther. 2020 Nov;19(11):2278-2287. doi: 10.1158/1535-7163.MCT-19-1141. Epub 2020 Sep 17. PMID: 32943543.
Huang W, Nebiolo C, Esbona K, Hu R, Lloyd R. Ki67 index and mitotic count: Correlation and variables affecting the accuracy of the quantification in endocrine/neuroendocrine tumors. Ann Diagn Pathol. 2020 Oct;48:151586. doi: 10.1016/j.anndiagpath.2020.151586. Epub 2020 Aug 15. Erratum in: Ann Diagn Pathol. 2022 Feb;56:151656. doi: 10.1016/j.anndiagpath.2020.151656. PMID: 32836178.
Narayanan D, Mandal R, Hardin H, Chanana V, Schwalbe M, Rosenbaum J, Buehler D, Lloyd RV. Long Non-coding RNAs in Pulmonary Neuroendocrine Neoplasms. Endocr Pathol. 2020 Sep;31(3):254-263. doi: 10.1007/s12022-020-09626-1. PMID: 32388776.
McDaniel NK, Iida M, Nickel KP, Longhurst CA, Fischbach SR, Rodems TS, Kranjac CA, Bo AY, Luo Q, Gallagher MM, Welke NB, Mitchell KR, Schulz AE, Eckers JC, Hu R, Salgia R, Hong S, Bruce JY, Kimple RJ, Wheeler DL. AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer. Clin Cancer Res. 2020 Aug 15;26(16):4349-4359. doi: 10.1158/1078-0432.CCR-19-3142. Epub 2020 May 21. PMID: 32439698; PMCID: PMC7442604.
Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Mol Oncol. 2020 Aug;14(8):1898-1909. doi: 10.1002/1878-0261.12687. Epub 2020 May 19. PMID: 32255253; PMCID: PMC7400789.
Popovics P, Awadallah WN, Kohrt SE, Case TC, Miller NL, Ricke EA, Huang W, Ramirez-Solano M, Liu Q, Vezina CM, Matusik RJ, Ricke WA, Grabowska MM. Prostatic osteopontin expression is associated with symptomatic benign prostatic hyperplasia. Prostate. 2020 Jul;80(10):731-741. doi: 10.1002/pros.23986. Epub 2020 May 1. PMID: 32356572; PMCID: PMC7485377.
Fogg KC, Renner CM, Christian H, Walker A, Marty-Santos L, Khan A, Olson WR, Parent C, O’Shea A, Wellik DM, Weisman PS, Kreeger PK. Ovarian Cells Have Increased Proliferation in Response to Heparin-Binding Epidermal Growth Factor as Collagen Density Increases. Tissue Eng Part A. 2020 Jul;26(13-14):747-758. doi: 10.1089/ten.tea.2020.0001. Epub 2020 Jun 25. PMID: 32598229; PMCID: PMC7398436.
Oikawa K, Ver Hoeve JN, Teixeira LBC, Snyder KC, Kiland JA, Ellinwood NM, McLellan GJ. Sub-region-Specific Optic Nerve Head Glial Activation in Glaucoma. Mol Neurobiol. 2020 Jun;57(6):2620-2638. doi: 10.1007/s12035-020-01910-9. Epub 2020 Apr 7. PMID: 32266645; PMCID: PMC7282894.
Fowler AM, Salem K, DeGrave M, Ong IM, Rassman S, Powers GL, Kumar M, Michel CJ, Mahajan AM. Progesterone Receptor Gene Variants in Metastatic Estrogen Receptor Positive Breast Cancer. Horm Cancer. 2020 Apr;11(2):63-75. doi: 10.1007/s12672-020-00377-3. Epub 2020 Jan 16. PMID: 31942683; PMCID: PMC7152560.
Berger AJ, Renner CM, Hale I, Yang X, Ponik SM, Weisman PS, Masters KS, Kreeger PK. Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling. Matrix Biol. 2020 Jan;85-86:80-93. doi: 10.1016/j.matbio.2019.07.006. Epub 2019 Jul 16. PMID: 31323325; PMCID: PMC6962577.
2019
Vellky JE, Bauman TM, Ricke EA, Huang W, Ricke WA. Incidence of androgen receptor and androgen receptor variant 7 coexpression in prostate cancer. Prostate. 2019 Dec;79(16):1811-1822. doi: 10.1002/pros.23906. Epub 2019 Sep 10. PMID: 31503366; PMCID: PMC7339117.
Wang Y, Hardin H, Chu YH, Esbona K, Zhang R, Lloyd RV. Long Non-coding RNA Expression in Anaplastic Thyroid Carcinomas. Endocr Pathol. 2019 Dec;30(4):262-269. doi: 10.1007/s12022-019-09589-y. PMID: 31468286.
Sheibani N, Wang S, Darjatmoko SR, Fisk DL, Shahi PK, Pattnaik BR, Sorenson CM, Bhowmick R, Volpert OV, Albert DM, Melgar-Asensio I, Henkin J. Novel anti-angiogenic PEDF-derived small peptides mitigate choroidal neovascularization. Exp Eye Res. 2019 Nov;188:107798. doi: 10.1016/j.exer.2019.107798. Epub 2019 Sep 11. PMID: 31520600; PMCID: PMC7032632.
Wang S, Liu Y, Tan JW, Hu T, Zhang HF, Sorenson CM, Smith JA, Sheibani N. Tunicamycin-induced photoreceptor atrophy precedes degeneration of retinal capillaries with minimal effects on retinal ganglion and pigment epithelium cells. Exp Eye Res. 2019 Oct;187:107756. doi: 10.1016/j.exer.2019.107756. Epub 2019 Aug 14. PMID: 31421136; PMCID: PMC7412575.
Kumar M, Salem K, Michel C, Jeffery JJ, Yan Y, Fowler AM. 18F-Fluoroestradiol PET Imaging of Activating Estrogen Receptor-α Mutations in Breast Cancer. J Nucl Med. 2019 Sep;60(9):1247-1252. doi: 10.2967/jnumed.118.224667. Epub 2019 Mar 8. PMID: 30850489; PMCID: PMC6735277.
Fogg KC, Olson WR, Miller JN, Khan A, Renner C, Hale I, Weisman PS, Kreeger PK. Alternatively activated macrophage-derived secretome stimulates ovarian cancer spheroid spreading through a JAK2/STAT3 pathway. Cancer Lett. 2019 Aug 28;458:92-101. doi: 10.1016/j.canlet.2019.05.029. Epub 2019 May 24. PMID: 31129149; PMCID: PMC6659112.
Zaitoun IS, Wintheiser CM, Jamali N, Wang S, Suscha A, Darjatmoko SR, Schleck K, Hanna BA, Lindner V, Sheibani N, Sorenson CM. Bcl-2 Expression in Pericytes and Astrocytes Impacts Vascular Development and Homeostasis. Sci Rep. 2019 Jul 4;9(1):9700. doi: 10.1038/s41598-019-45915-4. PMID: 31273232; PMCID: PMC6609701.
Sehgal PD, Bauman TM, Nicholson TM, Vellky JE, Ricke EA, Tang W, Xu W, Huang W, Ricke WA. Tissue-specific quantification and localization of androgen and estrogen receptors in prostate cancer. Hum Pathol. 2019 Jul;89:99-108. doi: 10.1016/j.humpath.2019.04.009. Epub 2019 May 3. PMID: 31054895; PMCID: PMC6642018.
Jamali N, Song YS, Sorenson CM, Sheibani N. 1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors. FASEB Bioadv. 2019 Jul;1(7):415-434. doi: 10.1096/fba.2018-00067. Epub 2019 May 3. PMID: 31396585; PMCID: PMC6687334.
Falero-Perez J, Sorenson CM, Sheibani N. Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. Am J Physiol Cell Physiol. 2019 Jun 1;316(6):C767-C781. doi: 10.1152/ajpcell.00021.2019. Epub 2019 Mar 20. PMID: 30892936; PMCID: PMC6620579.
Vellky JE, Ricke EA, Huang W, Ricke WA. Expression and Localization of DDX3 in Prostate Cancer Progression and Metastasis. Am J Pathol. 2019 Jun;189(6):1256-1267. doi: 10.1016/j.ajpath.2019.02.011. Epub 2019 Mar 27. PMID: 30926334; PMCID: PMC6547056.
Sharick JT, Jeffery JJ, Karim MR, Walsh CM, Esbona K, Cook RS, Skala MC. Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids. Neoplasia. 2019 Jun;21(6):615-626. doi: 10.1016/j.neo.2019.04.004. Epub 2019 May 9. PMID: 31078067; PMCID: PMC6514366.
Yu Q, Hardin H, Chu YH, Rehrauer W, Lloyd RV. Parathyroid Neoplasms: Immunohistochemical Characterization and Long Noncoding RNA (lncRNA) Expression. Endocr Pathol. 2019 Jun;30(2):96-105. doi: 10.1007/s12022-019-9578-3. PMID: 31119524.
Liu TT, Thomas S, Mclean DT, Roldan-Alzate A, Hernando D, Ricke EA, Ricke WA. Prostate enlargement and altered urinary function are part of the aging process. Aging (Albany NY). 2019 May 13;11(9):2653-2669. doi: 10.18632/aging.101938. PMID: 31085797; PMCID: PMC6535061.
Wan J, Block S, Scribano CM, Thiry R, Esbona K, Audhya A, Weaver BA. Mad1 destabilizes p53 by preventing PML from sequestering MDM2. Nat Commun. 2019 Apr 4;10(1):1540. doi: 10.1038/s41467-019-09471-9. PMID: 30948704; PMCID: PMC6449396.
Ren J, Zhou T, Pilli VSS, Phan N, Wang Q, Gupta K, Liu Z, Sheibani N, Liu B. Novel Paracrine Functions of Smooth Muscle Cells in Supporting Endothelial Regeneration Following Arterial Injury. Circ Res. 2019 Apr 12;124(8):1253-1265. doi: 10.1161/CIRCRESAHA.118.314567. PMID: 30739581; PMCID: PMC6459708.
Spurgeon ME, Uberoi A, McGregor SM, Wei T, Ward-Shaw E, Lambert PF. A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract. mBio. 2019 Mar 5;10(2):e00180-19. doi: 10.1128/mBio.00180-19. PMID: 30837335; PMCID: PMC6401479.
Roy M, Buehler DG, Zhang R, Schwalbe ML, Baus RM, Salamat MS, Lloyd RV, Rosenbaum JN. Expression of Insulinoma-Associated Protein 1 (INSM1) and Orthopedia Homeobox (OTP) in Tumors with Neuroendocrine Differentiation at Rare Sites. Endocr Pathol. 2019 Mar;30(1):35-42. doi: 10.1007/s12022-018-9559-y. PMID: 30523500.
Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H. Proproliferative function of adaptor protein GRB10 in prostate carcinoma. FASEB J. 2019 Mar;33(3):3198-3211. doi: 10.1096/fj.201800265RR. Epub 2018 Oct 31. Erratum in: FASEB J. 2023 Feb;37(2):e22754. doi: 10.1096/fsb2.22754. PMID: 30379590; PMCID: PMC6404554.
Chu YH, Hardin H, Eickhoff J, Lloyd RV. In Situ Hybridization Analysis of Long Non-coding RNAs MALAT1 and HOTAIR in Gastroenteropancreatic Neuroendocrine Neoplasms. Endocr Pathol. 2019 Mar;30(1):56-63. doi: 10.1007/s12022-018-9564-1. PMID: 30600442.
Mezu-Ndubuisi OJ, Wang Y, Schoephoerster J, Falero-Perez J, Zaitoun IS, Sheibani N, Gong S. Intravitreal Delivery of VEGF-A165-loaded PLGA Microparticles Reduces Retinal Vaso-Obliteration in an In Vivo Mouse Model of Retinopathy of Prematurity. Curr Eye Res. 2019 Mar;44(3):275-286. doi: 10.1080/02713683.2018.1542736. Epub 2018 Nov 9. PMID: 30383455; PMCID: PMC6661072.
Yang RK, Zhao P, Lu C, Luo J, Hu R. Expression pattern of androgen receptor and AR-V7 in androgen-deprivation therapy-naïve salivary duct carcinomas. Hum Pathol. 2019 Feb;84:173-182. doi: 10.1016/j.humpath.2018.09.009. Epub 2018 Sep 26. PMID: 30267779; PMCID: PMC7098468.
Falero-Perez J, Larsen MC, Teixeira LBC, Zhang HF, Lindner V, Sorenson CM, Jefcoate CR, Sheibani N. Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis. Trends Dev Biol. 2019;12:1-12. PMID: 32255961; PMCID: PMC7120807.
2018
Chamcheu JC, Siddiqui IA, Adhami VM, Esnault S, Bharali DJ, Babatunde AS, Adame S, Massey RJ, Wood GS, Longley BJ, Mousa SA, Mukhtar H. Chitosan-based nanoformulated (-)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis. Int J Nanomedicine. 2018 Jul 20;13:4189-4206. doi: 10.2147/IJN.S165966. Erratum in: Int J Nanomedicine. 2023 May 11;18:2503-2505. doi: 10.2147/IJN.S416060. PMID: 30057446; PMCID: PMC6059258.
Huebner SM, Helfrich KK, Saini N, Blohowiak SE, Cheng AA, Kling PJ, Smith SM. Dietary Iron Fortification Normalizes Fetal Hematology, Hepcidin, and Iron Distribution in a Rat Model of Prenatal Alcohol Exposure. Alcohol Clin Exp Res. 2018 Jun;42(6):1022-1033. doi: 10.1111/acer.13754. Epub 2018 May 19. PMID: 29672865; PMCID: PMC6317737.
Denu RA, Shabbir M, Nihal M, Singh CK, Longley BJ, Burkard ME, Ahmad N. Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma. Mol Cancer Res. 2018 Mar;16(3):517-527. doi: 10.1158/1541-7786.MCR-17-0197. Epub 2018 Jan 12. PMID: 29330283; PMCID: PMC5835182.
Zhang R, Hardin H, Huang W, Buehler D, Lloyd RV. Long Non-coding RNA Linc-ROR Is Upregulated in Papillary Thyroid Carcinoma. Endocr Pathol. 2018 Mar;29(1):1-8. doi: 10.1007/s12022-017-9507-2. PMID: 29280051.
Esbona K, Yi Y, Saha S, Yu M, Van Doorn RR, Conklin MW, Graham DS, Wisinski KB, Ponik SM, Eliceiri KW, Wilke LG, Keely PJ. The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients. Am J Pathol. 2018 Mar;188(3):559-573. doi: 10.1016/j.ajpath.2017.10.025. PMID: 29429545; PMCID: PMC5963475.
Rodríguez CI, Castro-Pérez E, Longley BJ, Setaluri V. Elevated cyclic AMP levels promote BRAFCA/Pten-/-mouse melanoma growth but pCREB is negatively correlated with human melanoma progression. Cancer Lett. 2018 Feb 1;414:268-277. doi: 10.1016/j.canlet.2017.11.027. Epub 2017 Nov 24. PMID: 29179997; PMCID: PMC5743623.
Rush PS, Rosenbaum JN, Roy M, Baus RM, Bennett DD, Lloyd RV. Insulinoma-associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma). J Cutan Pathol. 2018 Feb;45(2):129-135. doi: 10.1111/cup.13079. Epub 2017 Dec 17. PMID: 29148079.
2017
Damodaran S, Damaschke N, Gawdzik J, Yang B, Shi C, Allen GO, Huang W, Denu J, Jarrard D. Dysregulation of Sirtuin 2 (SIRT2) and histone H3K18 acetylation pathways associates with adverse prostate cancer outcomes. BMC Cancer. 2017 Dec 20;17(1):874. doi: 10.1186/s12885-017-3853-9. PMID: 29262808; PMCID: PMC5738829.
Connor JP, Esbona K, Matkowskyj KA. AKR1B10 expression by immunohistochemistry in surgical resections and fine needle aspiration cytology material in patients with cystic pancreatic lesions; potential for improved nonoperative diagnosis. Hum Pathol. 2017 Dec;70:77-83. doi: 10.1016/j.humpath.2017.10.006. Epub 2017 Oct 24. PMID: 29079172.
Mandal R, Hardin H, Baus R, Rehrauer W, Lloyd RV. Analysis of miR-96 and miR-133a Expression in Gastrointestinal Neuroendocrine Neoplasms. Endocr Pathol. 2017 Dec;28(4):345-350. doi: 10.1007/s12022-017-9504-5. PMID: 29032398.
Shen AL, Moran SM, Glover EA, Teixeira LB, Bradfield CA. Retinal pathology in the PPCD1 mouse. PLoS One. 2017 Oct 5;12(10):e0185094. doi: 10.1371/journal.pone.0185094. PMID: 28981549; PMCID: PMC5628829.
Chu YH, Hardin H, Schneider DF, Chen H, Lloyd RV. MicroRNA-21 and long non-coding RNA MALAT1 are overexpressed markers in medullary thyroid carcinoma. Exp Mol Pathol. 2017 Oct;103(2):229-236. doi: 10.1016/j.yexmp.2017.10.002. Epub 2017 Oct 26. PMID: 29107050.
Garcia-Peterson LM, Ndiaye MA, Singh CK, Chhabra G, Huang W, Ahmad N. SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. Genes Cancer. 2017 Sep;8(9-10):701-712. doi: 10.18632/genesandcancer.153. PMID: 29234488; PMCID: PMC5724804.
Covach A, Patel S, Hardin H, Lloyd RV. Phosphorylated Mechanistic Target of Rapamycin (p-mTOR) and Noncoding RNA Expression in Follicular and Hürthle Cell Thyroid Neoplasm. Endocr Pathol. 2017 Sep;28(3):207-212. doi: 10.1007/s12022-017-9490-7. PMID: 28660408.
Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Hu R, Iida M, Nickel KP, Bruce JY, Wheeler DL, Kimple RJ. Cotargeting mTORC and EGFR Signaling as a Therapeutic Strategy in HNSCC. Mol Cancer Ther. 2017 Jul;16(7):1257-1268. doi: 10.1158/1535-7163.MCT-17-0115. Epub 2017 Apr 26. PMID: 28446642; PMCID: PMC5505754.
Pointer KB, Clark PA, Schroeder AB, Salamat MS, Eliceiri KW, Kuo JS. Association of collagen architecture with glioblastoma patient survival. J Neurosurg. 2017 Jun;126(6):1812-1821. doi: 10.3171/2016.6.JNS152797. Epub 2016 Sep 2. PMID: 27588592; PMCID: PMC5386834.
King SN, Woo JH, Tang S, Thibeault SL. Macrophage Response to Allogeneic Adipose Tissue-Derived Stromal Cells in Hyaluronan-Based Hydrogel in a Porcine Vocal Fold Injury Model. Ann Otol Rhinol Laryngol. 2017 Jun;126(6):463-477. doi: 10.1177/0003489417702923. Epub 2017 Apr 6. PMID: 28385042.
Matson DR, Xu J, Huffman L, Barroilhet L, Accola M, Rehrauer WM, Weisman P. KRAS and GNAS Co-Mutation in Metastatic Low-Grade Appendiceal Mucinous Neoplasm (LAMN) to the Ovaries: A Practical Role for Next-Generation Sequencing. Am J Case Rep. 2017 May 20;18:558-562. doi: 10.12659/ajcr.903581. PMID: 28526814; PMCID: PMC5447665.
Jang S, Yu XM, Montemayor-Garcia C, Ahmed K, Weinlander E, Lloyd RV, Dammalapati A, Marshall D, Prudent JR, Chen H. Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes. Oncotarget. 2017 Apr 11;8(15):24457-24468. doi: 10.18632/oncotarget.14904. PMID: 28160550; PMCID: PMC5421862.
Imaizumi M, Li-Jessen NY, Sato Y, Yang DT, Thibeault SL. Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering. Ann Otol Rhinol Laryngol. 2017 Apr;126(4):304-314. doi: 10.1177/0003489417691296. Epub 2017 Feb 12. PMID: 28290232.
Pili R, Liu G, Chintala S, Verheul H, Rehman S, Attwood K, Lodge MA, Wahl R, Martin JI, Miles KM, Paesante S, Adelaiye R, Godoy A, King S, Zwiebel J, Carducci MA. Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial. Br J Cancer. 2017 Mar 28;116(7):874-883. doi: 10.1038/bjc.2017.33. Epub 2017 Feb 21. PMID: 28222071; PMCID: PMC5379145.
Wilking-Busch MJ, Ndiaye MA, Huang W, Ahmad N. Expression profile of SIRT2 in human melanoma and implications for sirtuin-based chemotherapy. Cell Cycle. 2017 Mar 19;16(6):574-577. doi: 10.1080/15384101.2017.1288323. Epub 2017 Feb 6. PMID: 28166441; PMCID: PMC5384585.
Somnay YR, Yu XM, Lloyd RV, Leverson G, Aburjania Z, Jang S, Jaskula-Sztul R, Chen H. Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosis. Cancer. 2017 Mar 1;123(5):769-782. doi: 10.1002/cncr.30403. Epub 2016 Nov 2. PMID: 27861750; PMCID: PMC5319883.
Zhang R, Hardin H, Huang W, Chen J, Asioli S, Righi A, Maletta F, Sapino A, Lloyd RV. MALAT1 Long Non-coding RNA Expression in Thyroid Tissues: Analysis by In Situ Hybridization and Real-Time PCR. Endocr Pathol. 2017 Mar;28(1):7-12. doi: 10.1007/s12022-016-9453-4. PMID: 27696303; PMCID: PMC5313332.
Blute ML Jr, Damaschke N, Wagner J, Yang B, Gleave M, Fazli L, Shi F, Abel EJ, Downs TM, Huang W, Jarrard DF. Persistence of senescent prostate cancer cells following prolonged neoadjuvant androgen deprivation therapy. PLoS One. 2017 Feb 24;12(2):e0172048. doi: 10.1371/journal.pone.0172048. PMID: 28234906; PMCID: PMC5325224.
Johnson MD, Stone B, Thibodeau BJ, Baschnagel AM, Galoforo S, Fortier LE, Ketelsen B, Ahmed S, Kelley Z, Hana A, Wilson TG, Robertson JM, Jury RP, Wilson GD. The significance of Trk receptors in pancreatic cancer. Tumour Biol. 2017 Feb;39(2):1010428317692256. doi: 10.1177/1010428317692256. PMID: 28218045
Cholewa BD, Ndiaye MA, Huang W, Liu X, Ahmad N. Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo. Cancer Lett. 2017 Jan 28;385:179-187. doi: 10.1016/j.canlet.2016.10.025. Epub 2016 Oct 25. PMID: 27793694; PMCID: PMC5171235.
Barcus CE, O’Leary KA, Brockman JL, Rugowski DE, Liu Y, Garcia N, Yu M, Keely PJ, Eliceiri KW, Schuler LA. Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells. Breast Cancer Res. 2017 Jan 19;19(1):9. doi: 10.1186/s13058-017-0801-1. PMID: 28103936; PMCID: PMC5244528.
Pointer KB, Clark PA, Eliceiri KW, Salamat MS, Robertson GA, Kuo JS. Administration of Non-Torsadogenic human Ether-à-go-go-Related Gene Inhibitors Is Associated with Better Survival for High hERG-Expressing Glioblastoma Patients. Clin Cancer Res. 2017 Jan 1;23(1):73-80. doi: 10.1158/1078-0432.CCR-15-3169. Epub 2016 Sep 15. PMID: 27635088; PMCID: PMC5627655.
Swick AD, Stein AP, McCulloch TM, Hartig GK, Ong IM, Sampene E, Prabakaran PJ, Liu CZ, Kimple RJ. Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts. Oral Oncol. 2017 Jan;64:65-72. doi: 10.1016/j.oraloncology.2016.11.017. Epub 2016 Dec 8. PMID: 28024726; PMCID: PMC5218527.
2016
Xu J, Hardin H, Zhang R, Sundling K, Buehler D, Lloyd RV. Stage-Specific Embryonic Antigen-1 (SSEA-1) Expression in Thyroid Tissues. Endocr Pathol. 2016 Dec;27(4):271-275. doi: 10.1007/s12022-016-9448-1. PMID: 27550342; PMCID: PMC5107349.
Drifka CR, Loeffler AG, Mathewson K, Keikhosravi A, Eickhoff JC, Liu Y, Weber SM, Kao WJ, Eliceiri KW. Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection. Oncotarget. 2016 Nov 15;7(46):76197-76213. doi: 10.18632/oncotarget.12772. PMID: 27776346; PMCID: PMC5342807.
Bauman TM, Huang W, Lee MH, Abel EJ. Neovascularity as a prognostic marker in renal cell carcinoma. Hum Pathol. 2016 Nov;57:98-105. doi: 10.1016/j.humpath.2016.07.005. Epub 2016 Jul 17. PMID: 27436827.
Jarrard D, Konety B, Huang W, Downs T, Kolesar J, Kim KM, Havighurst T, Slaton J, House MG, Parnes HL, Bailey HH. Phase IIa, randomized placebo-controlled trial of single high dose cholecalciferol (vitamin D3) and daily Genistein (G-2535) versus double placebo in men with early stage prostate cancer undergoing prostatectomy. Am J Clin Exp Urol. 2016 Sep 20;4(2):17-27. PMID: 27766277; PMCID: PMC5069272.
Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran PJ, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab. Mol Cancer Ther. 2016 Sep;15(9):2175-86. doi: 10.1158/1535-7163.MCT-16-0012. Epub 2016 Jul 15. PMID: 27422810; PMCID: PMC5010956.
Katsumura KR, Ong IM, DeVilbiss AW, Sanalkumar R, Bresnick EH. GATA Factor-Dependent Positive-Feedback Circuit in Acute Myeloid Leukemia Cells. Cell Rep. 2016 Aug 30;16(9):2428-41. doi: 10.1016/j.celrep.2016.07.058. Epub 2016 Aug 18. PMID: 27545880; PMCID: PMC5154384.
Wang L, Zhao Z, Meyer MB, Saha S, Yu M, Guo A, Wisinski KB, Huang W, Cai W, Pike JW, Yuan M, Ahlquist P, Xu W. CARM1 Methylates Chromatin Remodeling Factor BAF155 to Enhance Tumor Progression and Metastasis. Cancer Cell. 2016 Jul 11;30(1):179-180. doi: 10.1016/j.ccell.2016.06.013. Epub 2016 Jul 11. Erratum for: Cancer Cell. 2014 Jan 13;25(1):21-36. doi: 10.1016/j.ccr.2013.12.007. PMID: 27479032.
Gee JR, Saltzstein DR, Messing E, Kim K, Kolesar J, Huang W, Havighurst TC, Harris L, Wollmer BW, Jarrard D, House M, Parnes H, Bailey HH. Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy. Eur J Cancer Prev. 2016 Jul;25(4):312-20. doi: 10.1097/CEJ.0000000000000189. PMID: 26313229.
Wisinski KB, Tevaarwerk AJ, Burkard ME, Rampurwala M, Eickhoff J, Bell MC, Kolesar JM, Flynn C, Liu G. Phase I Study of an AKT Inhibitor (MK-2206) Combined with Lapatinib in Adult Solid Tumors Followed by Dose Expansion in Advanced HER2+ Breast Cancer. Clin Cancer Res. 2016 Jun 1;22(11):2659-67. doi: 10.1158/1078-0432.CCR-15-2365. Epub 2016 Mar 29. PMID: 27026198; PMCID: PMC4891227.
Hardin H, Yu XM, Harrison AD, Larrain C, Zhang R, Chen J, Chen H, Lloyd RV. Generation of Novel Thyroid Cancer Stem-Like Cell Clones: Effects of Resveratrol and Valproic Acid. Am J Pathol. 2016 Jun;186(6):1662-73. doi: 10.1016/j.ajpath.2016.02.003. Epub 2016 Apr 7. PMID: 27060227; PMCID: PMC6136064.
Bauman TM, Vezina CM, Ricke EA, Halberg RB, Huang W, Peterson RE, Ricke WA. Expression and colocalization of β-catenin and lymphoid enhancing factor-1 in prostate cancer progression. Hum Pathol. 2016 May;51:124-33. doi: 10.1016/j.humpath.2015.12.024. Epub 2016 Jan 19. PMID: 27067790; PMCID: PMC4830919.
Bauman TM, Ricke EA, Drew SA, Huang W, Ricke WA. Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging. J Vis Exp. 2016 Apr 8;(110):53837. doi: 10.3791/53837. PMID: 27167094; PMCID: PMC4913774.
George J, Nihal M, Singh CK, Zhong W, Liu X, Ahmad N. Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma. J Invest Dermatol. 2016 Apr;136(4):809-818. doi: 10.1016/j.jid.2015.12.026. Epub 2015 Dec 29. PMID: 26743598; PMCID: PMC4808399.
Zumwalde NA, Haag JD, Sharma D, Mirrielees JA, Wilke LG, Gould MN, Gumperz JE. Analysis of Immune Cells from Human Mammary Ductal Epithelial Organoids Reveals Vδ2+ T Cells That Efficiently Target Breast Carcinoma Cells in the Presence of Bisphosphonate. Cancer Prev Res (Phila). 2016 Apr;9(4):305-16. doi: 10.1158/1940-6207.CAPR-15-0370-T. Epub 2016 Jan 25. PMID: 26811335; PMCID: PMC4818696.
Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Res. 2016 Mar 22;18(1):35. doi: 10.1186/s13058-016-0695-3. PMID: 27000374; PMCID: PMC4802888.
Yu W, Denu RA, Krautkramer KA, Grindle KM, Yang DT, Asimakopoulos F, Hematti P, Denu JM. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies. J Biol Chem. 2016 Feb 12;291(7):3268-79. doi: 10.1074/jbc.M115.702076. Epub 2015 Dec 2. PMID: 26631723; PMCID: PMC4751373.
Francis DM, Huang S, Armstrong EA, Werner LR, Hullett C, Li C, Morris ZS, Swick AD, Kragh M, Lantto J, Kimple RJ, Harari PM. Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models. Clin Cancer Res. 2016 Feb 1;22(3):633-43. doi: 10.1158/1078-0432.CCR-15-1664. Epub 2015 Sep 29. PMID: 26420857.
Gertz RJ, Nikiforov Y, Rehrauer W, McDaniel L, Lloyd RV. Mutation in BRAF and Other Members of the MAPK Pathway in Papillary Thyroid Carcinoma in the Pediatric Population. Arch Pathol Lab Med. 2016 Feb;140(2):134-9. doi: 10.5858/arpa.2014-0612-OA. PMID: 26910217; PMCID: PMC8006595.
Denu RA, Zasadil LM, Kanugh C, Laffin J, Weaver BA, Burkard ME. Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer. BMC Cancer. 2016 Jan 29;16:47. doi: 10.1186/s12885-016-2083-x. PMID: 26832928; PMCID: PMC4734858.
Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin JJ, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer. Mol Cancer Ther. 2016 Jan;15(1):48-59. doi: 10.1158/1535-7163.MCT-15-0527. Epub 2015 Nov 19. PMID: 26586723; PMCID: PMC4707107.
2015
Bauman TM, Becka AJ, Sehgal PD, Huang W, Ricke WA. SIGIRR/TIR8, an important regulator of TLR4 and IL-1R-mediated NF-κB activation, predicts biochemical recurrence after prostatectomy in low-grade prostate carcinomas. Hum Pathol. 2015 Nov;46(11):1744-51. doi: 10.1016/j.humpath.2015.07.015. Epub 2015 Jul 29. PMID: 26344417; PMCID: PMC4661098.
Drifka CR, Tod J, Loeffler AG, Liu Y, Thomas GJ, Eliceiri KW, Kao WJ. Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis. Mod Pathol. 2015 Nov;28(11):1470-80. doi: 10.1038/modpathol.2015.97. Epub 2015 Sep 4. PMID: 26336888.
Zeng H, Xu W. Ctr9, a key subunit of PAFc, affects global estrogen signaling and drives ERα-positive breast tumorigenesis. Genes Dev. 2015 Oct 15;29(20):2153-67. doi: 10.1101/gad.268722.115. PMID: 26494790; PMCID: PMC4617979.
Rosenbaum JN, Guo Z, Baus RM, Werner H, Rehrauer WM, Lloyd RV. INSM1: A Novel Immunohistochemical and Molecular Marker for Neuroendocrine and Neuroepithelial Neoplasms. Am J Clin Pathol. 2015 Oct;144(4):579-91. doi: 10.1309/AJCPGZWXXBSNL4VD. PMID: 26386079.
Artz NS, Haufe WM, Hooker CA, Hamilton G, Wolfson T, Campos GM, Gamst AC, Schwimmer JB, Sirlin CB, Reeder SB. Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1.5T and 3T in obese subjects. J Magn Reson Imaging. 2015 Sep;42(3):811-7. doi: 10.1002/jmri.24842. Epub 2015 Jan 23. PMID: 25620624; PMCID: PMC4803480.
Huang W, Eickhoff JC, Mehraein-Ghomi F, Church DR, Wilding G, Basu HS. Expression of spermidine/spermine N(1) -acetyl transferase (SSAT) in human prostate tissues is related to prostate cancer progression and metastasis. Prostate. 2015 Aug 1;75(11):1150-9. doi: 10.1002/pros.22996. Epub 2015 Apr 20. PMID: 25893668; PMCID: PMC4475436Bauman TM, Ewald JA, Huang W, Ricke WA. CD147 expression predicts biochemical recurrence after prostatectomy independent of histologic and pathologic features. BMC Cancer. 2015 Jul 25;15:549. doi: 10.1186/s12885-015-1559-4. PMID: 26209327; PMCID: PMC4514016.
Shanle EK, Onitilo AA, Huang W, Kim K, Zang C, Engel JM, Xu W, Wisinski KB. Prognostic significance of full-length estrogen receptor beta expression in stage I-III triple negative breast cancer. Am J Transl Res. 2015 Jul 15;7(7):1246-59. PMID: 26328009; PMCID: PMC4548317.
Shlensky D, Mirrielees JA, Zhao Z, Wang L, Mahajan A, Yu M, Sherer NM, Wilke LG, Xu W. Differential CARM1 Isoform Expression in Subcellular Compartments and among Malignant and Benign Breast Tumors. PLoS One. 2015 Jun 1;10(6):e0128143. doi: 10.1371/journal.pone.0128143. Erratum in: PLoS One. 2015 Jun 25;10(6):e0131955. doi: 10.1371/journal.pone.0131955. PMID: 26030442; PMCID: PMC4451767.
Fakhraldeen SA, Clark RJ, Roopra A, Chin EN, Huang W, Castorino J, Wisinski KB, Kim T, Spiegelman VS, Alexander CM. Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor Cells. J Biol Chem. 2015 May 22;290(21):13386-400. doi: 10.1074/jbc.M115.655175. Epub 2015 Apr 10. PMID: 25861986; PMCID: PMC4505587.
Guo Z, Hardin H, Montemayor-Garcia C, Asioli S, Righi A, Maletta F, Sapino A, Lloyd RV. In Situ Hybridization Analysis of miR-146b-5p and miR-21 in Thyroid Nodules: Diagnostic Implications. Endocr Pathol. 2015 May;26(2):157-63. doi: 10.1007/s12022-015-9363-x. PMID: 25771986.
Wagner J, Damaschke N, Yang B, Truong M, Guenther C, McCormick J, Huang W, Jarrard D. Overexpression of the novel senescence marker β-galactosidase (GLB1) in prostate cancer predicts reduced PSA recurrence. PLoS One. 2015 Apr 15;10(4):e0124366. doi: 10.1371/journal.pone.0124366. PMID: 25876105; PMCID: PMC4398352.
Kuo PY, Leshchenko VV, Fazzari MJ, Perumal D, Gellen T, He T, Iqbal J, Baumgartner-Wennerholm S, Nygren L, Zhang F, Zhang W, Suh KS, Goy A, Yang DT, Chan WC, Kahl BS, Verma AK, Gascoyne RD, Kimby E, Sander B, Ye BH, Melnick AM, Parekh S. High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma. Oncogene. 2015 Mar 5;34(10):1231-40. doi: 10.1038/onc.2014.44. Epub 2014 Mar 31. PMID: 24681958; PMCID: PMC4511176.
Jaskula-Sztul R, Eide J, Tesfazghi S, Dammalapati A, Harrison AD, Yu XM, Scheinebeck C, Winston-McPherson G, Kupcho KR, Robers MB, Hundal AK, Tang W, Chen H. Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction. Mol Cancer Ther. 2015 Feb;14(2):499-512. doi: 10.1158/1535-7163.MCT-14-0073. Epub 2014 Dec 15. PMID: 25512616; PMCID: PMC4326595.
2014
Bauman TM, Vezina CM, Huang W, Marker PC, Peterson RE, Ricke WA. Beta-catenin is elevated in human benign prostatic hyperplasia specimens compared to histologically normal prostate tissue. Am J Clin Exp Urol. 2014 Dec 25;2(4):313-22. PMID: 25606577; PMCID: PMC4297327.
Damaschke NA, Yang B, Blute ML Jr, Lin CP, Huang W, Jarrard DF. Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer. Neoplasia. 2014 Dec;16(12):1018-27. doi: 10.1016/j.neo.2014.10.003. PMID: 25499215; PMCID: PMC4309256.
Bauman TM, Nicholson TM, Abler LL, Eliceiri KW, Huang W, Vezina CM, Ricke WA. Characterization of fibrillar collagens and extracellular matrix of glandular benign prostatic hyperplasia nodules. PLoS One. 2014 Oct 2;9(10):e109102. doi: 10.1371/journal.pone.0109102. PMID: 25275645; PMCID: PMC4183548.
Hardin H, Guo Z, Shan W, Montemayor-Garcia C, Asioli S, Yu XM, Harrison AD, Chen H, Lloyd RV. The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. Am J Pathol. 2014 Aug;184(8):2342-54. doi: 10.1016/j.ajpath.2014.04.011. Epub 2014 Jun 17. PMID: 24946010; PMCID: PMC4116695.
Singh CK, Ndiaye MA, Siddiqui IA, Nihal M, Havighurst T, Kim K, Zhong W, Mukhtar H, Ahmad N. Methaneseleninic acid and γ-Tocopherol combination inhibits prostate tumor growth in Vivo in a xenograft mouse model. Oncotarget. 2014 Jun 15;5(11):3651-61. doi: 10.18632/oncotarget.1979. PMID: 25004451; PMCID: PMC4116510.
Bauman TM, Sehgal PD, Johnson KA, Pier T, Bruskewitz RC, Ricke WA, Huang W. Finasteride treatment alters tissue specific androgen receptor expression in prostate tissues. Prostate. 2014 Jun;74(9):923-32. doi: 10.1002/pros.22810. Epub 2014 Apr 30. PMID: 24789081; PMCID: PMC4137476.
Wu J, Salva KA, Stutz N, Longley BJ, Spiegelman VS, Wood GS. Quantitative gene analysis of methylation and expression (Q-GAME) in fresh or fixed cells and tissues. Exp Dermatol. 2014 May;23(5):304-9. doi: 10.1111/exd.12374. PMID: 24646432; PMCID: PMC4331060.
Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F. TPL2 kinase regulates the inflammatory milieu of the myeloma niche. Blood. 2014 May 22;123(21):3305-15. doi: 10.1182/blood-2014-02-554071. Epub 2014 Apr 10. PMID: 24723682; PMCID: PMC4046426.
Brand TM, Iida M, Dunn EF, Luthar N, Kostopoulos KT, Corrigan KL, Wleklinski MJ, Yang D, Wisinski KB, Salgia R, Wheeler DL. Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer. Mol Cancer Ther. 2014 May;13(5):1356-68. doi: 10.1158/1535-7163.MCT-13-1021. Epub 2014 Mar 14. Erratum in: Mol Cancer Ther. 2019 Apr;18(4):868. doi: 10.1158/1535-7163.MCT-18-1183. PMID: 24634415; PMCID: PMC4013210.
Abel EJ, Bauman TM, Weiker M, Shi F, Downs TM, Jarrard DF, Huang W. Analysis and validation of tissue biomarkers for renal cell carcinoma using automated high-throughput evaluation of protein expression. Hum Pathol. 2014 May;45(5):1092-9. doi: 10.1016/j.humpath.2014.01.008. Epub 2014 Jan 28. PMID: 24746216; PMCID: PMC4134351.
Clarkson BD, Ling C, Shi Y, Harris MG, Rayasam A, Sun D, Salamat MS, Kuchroo V, Lambris JD, Sandor M, Fabry Z. T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice. J Exp Med. 2014 Apr 7;211(4):595-604. doi: 10.1084/jem.20131377. Epub 2014 Mar 10. PMID: 24616379; PMCID: PMC3978271.
Rasmussen CA, Schlosser SJ, Allen-Hoffmann BL (2014) Morphogenesis of Biologically Active Interfollicular Epidermis from Human Embryonic Stem Cell-derived Keratinocytes. J Stem Cell Res Ther 4: 163. doi:10.4172/2157-7633.1000163
2013
Katzenberger RJ, Loewen CA, Wassarman DR, Petersen AJ, Ganetzky B, Wassarman DA. A Drosophila model of closed head traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4152-9. doi: 10.1073/pnas.1316895110. Epub 2013 Oct 14. PMID: 24127584; PMCID: PMC3816429.
Oberley MJ, Rajguru SA, Zhang C, Kim K, Shaw GR, Grindle KM, Kahl BS, Kanugh C, Laffin J, Yang DT. Immunohistochemical evaluation of MYC expression in mantle cell lymphoma. Histopathology. 2013 Oct;63(4):499-508. doi: 10.1111/his.12207. Epub 2013 Aug 8. PMID: 23926923; PMCID: PMC3871984.
Buehler D, Rush P, Hasenstein JR, Rice SR, Hafez GR, Longley BJ, Kozak KR. Expression of angiopoietin-TIE system components in angiosarcoma. Mod Pathol. 2013 Aug;26(8):1032-40. doi: 10.1038/modpathol.2013.43. Epub 2013 Apr 5. PMID: 23558570; PMCID: PMC3706492.
Nicholson TM, Sehgal PD, Drew SA, Huang W, Ricke WA. Sex steroid receptor expression and localization in benign prostatic hyperplasia varies with tissue compartment. Differentiation. 2013 Apr-Jun;85(4-5):140-9. doi: 10.1016/j.diff.2013.02.006. Epub 2013 Jun 20. PMID: 23792768; PMCID: PMC3729928.
Yang B, Bhusari S, Kueck J, Weeratunga P, Wagner J, Leverson G, Huang W, Jarrard DF. Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer. Neoplasia. 2013 Apr;15(4):399-408. doi: 10.1593/neo.13280. PMID: 23555185; PMCID: PMC3612912.
Slezak J, Truong M, Huang W, Jarrard D. HP1γ expression is elevated in prostate cancer and is superior to Gleason score as a predictor of biochemical recurrence after radical prostatectomy. BMC Cancer. 2013 Mar 23;13:148. doi: 10.1186/1471-2407-13-148. PMID: 23522301; PMCID: PMC3618256.
Huang W, Hennrick K, Drew S. A colorful future of quantitative pathology: validation of Vectra technology using chromogenic multiplexed immunohistochemistry and prostate tissue microarrays. Hum Pathol. 2013 Jan;44(1):29-38. doi: 10.1016/j.humpath.2012.05.009. Epub 2012 Aug 31. PMID: 22944297.
Desotelle J, Truong M, Ewald J, Weeratunga P, Yang B, Huang W, Jarrard D. CpG island hypermethylation frequently silences FILIP1L isoform 2 expression in prostate cancer. J Urol. 2013 Jan;189(1):329-35. doi: 10.1016/j.juro.2012.08.188. Epub 2012 Nov 20. PMID: 23174249; PMCID: PMC3581042.
Buehler D, Hardin H, Shan W, Montemayor-Garcia C, Rush PS, Asioli S, Chen H, Lloyd RV. Expression of epithelial-mesenchymal transition regulators SNAI2 and TWIST1 in thyroid carcinomas. Mod Pathol. 2013 Jan;26(1):54-61. doi: 10.1038/modpathol.2012.137. Epub 2012 Aug 17. PMID: 22899291; PMCID: PMC3559085.
2011
Yang N, Mosher R, Seo S, Beebe D, Friedl A. Syndecan-1 in breast cancer stroma fibroblasts regulates extracellular matrix fiber organization and carcinoma cell motility. Am J Pathol. 2011 Jan;178(1):325-35. doi: 10.1016/j.ajpath.2010.11.039. Epub 2010 Dec 23. PMID: 21224069; PMCID: PMC3069862.
Conklin MW, Eickhoff JC, Riching KM, Pehlke CA, Eliceiri KW, Provenzano PP, Friedl A, Keely PJ. Aligned collagen is a prognostic signature for survival in human breast carcinoma. Am J Pathol. 2011 Mar;178(3):1221-32. doi: 10.1016/j.ajpath.2010.11.076. PMID: 21356373; PMCID: PMC3070581.
Yang DT, Quann PJ, Petrich AM, Leith CP, Young KH, Kahl BS. Use of tissue microarray and automated quantitative analysis for screening and validation of potential biomarkers in mantle cell lymphoma. Appl Immunohistochem Mol Morphol. 2011 Jan;19(1):62-9. doi: 10.1097/PAI.0b013e3181ed47bc. PMID: 20881841; PMCID: PMC3040491.
2010
Wagoner MP, Gunsalus KT, Schoenike B, Richardson AL, Friedl A, Roopra A. The transcription factor REST is lost in aggressive breast cancer. PLoS Genet. 2010 Jun 10;6(6):e1000979. doi: 10.1371/journal.pgen.1000979. PMID: 20548947; PMCID: PMC2883591.
Maddodi N, Huang W, Havighurst T, Kim K, Longley BJ, Setaluri V. Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF. J Invest Dermatol. 2010 Jun;130(6):1657-67. doi: 10.1038/jid.2010.26. Epub 2010 Feb 25. PMID: 20182446; PMCID: PMC2869390.
Leshchenko VV, Kuo PY, Shaknovich R, Yang DT, Gellen T, Petrich A, Yu Y, Remache Y, Weniger MA, Rafiq S, Suh KS, Goy A, Wilson W, Verma A, Braunschweig I, Muthusamy N, Kahl BS, Byrd JC, Wiestner A, Melnick A, Parekh S. Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood. 2010 Aug 19;116(7):1025-34. doi: 10.1182/blood-2009-12-257485. Epub 2010 Apr 28. PMID: 20427703; PMCID: PMC2938124.
2009
Rahrmann EP, Collier LS, Knutson TP, Doyal ME, Kuslak SL, Green LE, Malinowski RL, Roethe L, Akagi K, Waknitz M, Huang W, Largaespada DA, Marker PC. Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen. Cancer Res. 2009 May 15;69(10):4388-97. doi: 10.1158/0008-5472.CAN-08-3901. Epub 2009 Apr 28. PMID: 19401450; PMCID: PMC2710962.
Thomas-Virnig CL, Centanni JM, Johnston CE, He LK, Schlosser SJ, Van Winkle KF, Chen R, Gibson AL, Szilagyi A, Li L, Shankar R, Allen-Hoffmann BL. Inhibition of multidrug-resistant Acinetobacter baumannii by nonviral expression of hCAP-18 in a bioengineered human skin tissue. Mol Ther. 2009 Mar;17(3):562-9. doi: 10.1038/mt.2008.289. Epub 2009 Feb 3. PMID: 19190595; PMCID: PMC2736055.
Huang W, Kanehira K, Drew S, Pier T. Oncocytoma can be differentiated from its renal cell carcinoma mimics by a panel of markers: an automated tissue microarray study. Appl Immunohistochem Mol Morphol. 2009 Jan;17(1):12-7. doi: 10.1097/PAI.0b013e318173e79d. PMID: 18769342.
2008
Sadow PM, Rumilla KM, Erickson LA, Lloyd RV. Stathmin expression in pheochromocytomas, paragangliomas, and in other endocrine tumors. Endocr Pathol. 2008 Summer;19(2):97-103. doi: 10.1007/s12022-008-9028-0. PMID: 18461287.
2006
Su G, Meyer K, Nandini CD, Qiao D, Salamat S, Friedl A. Glypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cells. Am J Pathol. 2006 Jun;168(6):2014-26. doi: 10.2353/ajpath.2006.050800. PMID: 16723715; PMCID: PMC1606624.
Rumilla KM, Erickson LA, Erickson AK, Lloyd RV. Galectin-4 expression in carcinoid tumors. Endocr Pathol. 2006 Fall;17(3):243-9. doi: 10.1385/ep:17:3:243. PMID: 17308361.
Ruebel KH, Leontovich AA, Jin L, Stilling GA, Zhang H, Qian X, Nakamura N, Scheithauer BW, Kovacs K, Lloyd RV. Patterns of gene expression in pituitary carcinomas and adenomas analyzed by high-density oligonucleotide arrays, reverse transcriptase-quantitative PCR, and protein expression. Endocrine. 2006 Jun;29(3):435-44. doi: 10.1385/ENDO:29:3:435. PMID: 16943582.
Baba F, Swartz K, van Buren R, Eickhoff J, Zhang Y, Wolberg W, Friedl A. Syndecan-1 and syndecan-4 are overexpressed in an estrogen receptor-negative, highly proliferative breast carcinoma subtype. Breast Cancer Res Treat. 2006 Jul;98(1):91-8. doi: 10.1007/s10549-005-9135-2. Epub 2006 Apr 25. PMID: 16636895.
Maeda T, Desouky J, Friedl A. Syndecan-1 expression by stromal fibroblasts promotes breast carcinoma growth in vivo and stimulates tumor angiogenesis. Oncogene. 2006 Mar 2;25(9):1408-12. doi: 10.1038/sj.onc.1209168. PMID: 16247452.
2005
Baiu DC, Barger B, Sandor M, Fabry Z, Hart MN. Autoantibodies to vascular smooth muscle are pathogenic for vasculitis. Am J Pathol. 2005 Jun;166(6):1851-60. doi: 10.1016/S0002-9440(10)62494-7. PMID: 15920169; PMCID: PMC1602413.
2002
Steiglitz BM, Keene DR, Greenspan DS. PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1. J Biol Chem. 2002 Dec 20;277(51):49820-30. doi:10.1074/jbc.M209891200. Epub 2002 Oct 20. PMID: 12393877.
Jarrard DF, Modder J, Fadden P, Fu V, Sebree L, Heisey D, Schwarze SR, Friedl A. Alterations in the p16/pRb cell cycle checkpoint occur commonly in primary and metastatic human prostate cancer. Cancer Lett. 2002 Nov 28;185(2):191-9. doi: 10.1016/s0304-3835(02)00282-3. PMID: 12169393.
2001
Hogan LH, Macvilay K, Barger B, Co D, Malkovska I, Fennelly G, Sandor M. Mycobacterium bovis strain bacillus Calmette-Guérin-induced liver granulomas contain a diverse TCR repertoire, but a monoclonal T cell population is sufficient for protective granuloma formation. J Immunol. 2001 May 15;166(10):6367-75. doi: 10.4049/jimmunol.166.10.6367. PMID: 11342661.