Research
Department of Pathology and Laboratory Medicine

TRIP Publications

  1. Zheng, C.; Allen, K.O.; Liu, T.; Solodin, N.M.; Meyer, M.B.; Salem, K.; Tsourkas, P.K.; McIlwain, S.J.; Vera, J.M.; Cromwell, E.R.; et al. Elevated GRHL2 Imparts Plasticity in ER-Positive Breast Cancer Cells. Cancers 2024, 16, 2906. Aug 21, 2024.
  2. Albertini,M.R.; Zuleger,C.L.; Ranheim, E.A.; Shiyanbola, O.; Sondel, P.M.; Morris, Z.S.; Eickhoff, J.; Newton, M.; Ong, I.M.; Schwartz, R.W.; Hayim, R.; Kurzman, I.D.; Michelle, T.; Vail, D.M. Administration of intratumoral GD2-directed interleukin-2immunocytokine and local radiation therapy to activate rejection of spontaneous canine melanoma. Melanoma Research 2024 Aug 1;34(4):307-318. PMID: 38768442.  link: https://journals.lww.com/melanomaresearch/abstract/2024/08000/administration_of_intratumoral_gd2_directed.3.aspx
  3. Lozar, T,; Laklouk, I.; Golfinos, A.E.; Gavrielatou, N., Xu, J.; et al. Stress Keratin 17 Is a Predictive Biomarker Inversely Associated with Response to Immune Check-Point Blockade in Head and Neck Squamous Cell Carcinomas and Beyond. Cancers. 2023, Oct, 9. https://doi.org/10.3390/cancers15194905
  4. Lechner, S.A.; Welsch, J.M.; Pahapill, N.K.; Kaldenberg, T.A.R.; Regenbaum, A.; Kelm-Nelson, C.A. Predictors of prodromal Parkinson’s disease in young adult Pink1-/- rats. Behav. Neurosci. 11 Sept 2022. Vol 16-2022. https://doi.org/10.3389/fnbeh.2022.867958
  5. Papadas A, Deb G, Cicala A, Officer A, Hope C, Pagenkopf A, Flietner E, Morrow ZT, Emmerich P, Wiesner J, Arauz G, Bansal V, Esbona K, Capitini CM, Matkowskyj KA, Deming DA, Politi K, Abrams SI, Harismendy O, Asimakopoulos F. Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment. Cell Rep. 2022 Aug 16;40(7):111201. doi: 10.1016/j.celrep.2022.111201. PMID: 35977482
  6. Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O’Regan R, McGregor SM, Fowler AM, Chappell RJ, Bugni TS, Burkard ME, Weaver BA. Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel. Sci Transl Med. 2021 Sep 8;13(610):eabd4811. doi: 10.1126/scitranslmed.abd4811. Epub 2021 Sep 8. PMID: 34516829
  7. Magee K, Marsh IR, Turek MM, Grudzinski J, Aluicio-Sarduy E, Engle JW, Kurzman ID, Zuleger CL, Oseid EA, Jaskowiak C, Albertini MR, Esbona K, Bednarz B, Sondel PM, Weichert JP, Morris ZS, Hernandez R, Vail DM. Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting. PLoS One. 2021 Aug 12;16(8):e0255798. doi: 10.1371/journal.pone.0255798. eCollection 2021. PMID: 34383787
  8. Shengqin Su, Gagan Chhabra, Mary A. Ndiaye, Chandra K. Singh, Ting Ye, Wei Huang, Colin N. Dewey, Vijayasaradhi Setaluri and Nihal Ahmad. PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways. Mol Cancer Ther Jan 2021;20:161–72. DOI: 10.1158/1535-7163.MCT-20-0654
  9. Huang W, Nebiolo C, Esbona K, Hu R, Lloyd R.Ann Diagn Pathol. 2020 Oct 30:151656. doi:
    1016/j.anndiagpath.2020.151656. Online ahead of print.PMID: 33132037
  10. Narayanan D, Mandal R, Hardin H, Chanana V, Schwalbe M, Rosenbaum J, Buehler D, Lloyd RV. Long Non-coding RNAs in Pulmonary Neuroendocrine Neoplasms. Endocr Pathol. 2020 May. doi: 10.1007/s12022-020-09626-1. PMID: 32388776
  11. Fowler AM, Salem K, DeGrave M, et al. Progesterone Receptor Gene Variants in Metastatic Estrogen Receptor Positive Breast Cancer. Hormones & Cancer. 2020 Apr;11(2):63-75. DOI: 10.1007/s12672-020-00377-3.
  12. Wiesner DL, Merkhofer RM, Ober C, Kujoth GC, Niu M, Keller NP, Gern JE, Brockman-Schneider RA, Evans MD, Jackson DJ, Warner T, Jarjour NN, Esnault SJ, Feldman MB, Freeman M, Mou H, Vyas JM, Klein BS. Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation. Cell Host Microbe. 2020 Apr 8;27(4):614-628.e6. doi: 10.1016/j.chom.2020.02.006
  13. Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Mol Oncol. 2020 Apr 7. doi: 10.1002/1878-0261.12687.
  14. Oikawa K, Ver Hoeve JN, Teixeira LBC, Snyder KC, Kiland JA, Ellinwood NM, McLellan GJ.Sub-region-Specific Optic Nerve Head Glial Activation in Glaucoma. Mol Neurobiol. 2020 Apr 7. doi: 10.1007/s12035-020-01910-9
  15. Qazi MS, McGregor SM. Combined use of SOX10 and GATA3 in mammary carcinoma. Pathol Res Pract. 2020 Feb;216(2):152801. doi: 10.1016/j.prp.2019.152801.
  16. Denu RA, Kaur G, Sass MM, Lakkaraju A, Burkard ME. Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition. Mol Cancer Res. 2020 Jan;18(1):33-45. doi: 10.1158/1541-7786.MCR-19-0509.
  17. Bowen RC, Lawson BM, Jody NM, Potter HD, Lucarelli MJ. The Programmed Death Pathway in Ocular Adnexal Sebaceous Carcinoma. Ophthalmic Plast Reconstr Surg. 2020 Jan/Feb;36(1):74-79. doi: 10.1097/IOP.0000000000001472
  18. Wang Y, Hardin H, Chu YH, Esbona K, Zhang R, Lloyd RV. Long Non-coding RNA Expression in Anaplastic Thyroid Carcinomas. Endocr Pathol. 2019 Dec;30(4):262-269. doi: 10.1007/s12022-019-09589-y. PMID: 31468286
  19. Vellky JE, Bauman TM, Ricke EA, Huang W, Ricke WA (2019). Incidence of Androgen Receptor and Androgen Receptor Variant 7 Coexpression in Prostate Cancer. 2019 Dec; 79(16)):1811-1822 [Epub 2019 Sep 10]. PMID: 31503366; DOI: 10.1002/pros.23906.
  20. Sheibani N, Wang S, Darjatmoko SR, Fisk DL, Shahi PK, Pattnaik BR, Sorenson CM, Bhowmick R, Volpert OV, Albert DM, Melgar-Asensio I, Henkin J. Novel anti-angiogenic PEDF-derived small peptides mitigate choroidal neovascularization. Exp Eye Res. 2019 Nov;188:107798. doi: 10.1016/j.exer.2019.107798.
  21. Tunicamycin-induced photoreceptor atrophy precedes degeneration of retinal capillaries with minimal effects on retinal ganglion and pigment epithelium cells. Wang S, Liu Y, Tan JW, Hu T, Zhang HF, Sorenson CM, Smith JA, Sheibani N. Exp Eye Res. 2019 Oct;187:107756. doi: 10.1016/j.exer.2019.107756.
  22. Jamali N, Song YS, Sorenson CM, Sheibani N. 1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors. FASEB Bioadv. 2019 Jul;1(7):415-434. doi: 10.1096/fba.2018-00067.
  23. Zaitoun IS, Wintheiser CM, Jamali N, Wang S, Suscha A, Darjatmoko SR, Schleck K, Hanna BA, Lindner V, Sheibani N, Sorenson CM. Bcl-2 Expression in Pericytes and Astrocytes Impacts Vascular Development and Homeostasis. Sci Rep. 2019 Jul 4;9(1):9700. doi: 10.1038/s41598-019-45915-4.
  24. Sehgal PD, Bauman TM, Nicholson TM, Vellky JE, Ricke EA, Tang W, Xu W, Huang W, Ricke WA (2019). Tissue-specific Quantification and Localization of Androgen and Estrogen Receptors in Prostate Cancer. Hum Pathol. 2019 Jul; 89:99-108 [Epub 2019 May 3]. PMID: 31054895; PMC6642018; DOI: 10.1016/j.humpath.2019.04.009.
  25. Vellky JE, Ricke EA, Huang W, Ricke WA (2019). Expression and Localization of DDX3 in Prostate Cancer Progression and Metastasis. Am J Pathol. 2019 Jun; 189(6):1256-1267 [Epub 2019 Mar 27]. PMID: 30926334; PMC6547056; DOI: 10.1016/j.ajpath.2019.02.011.
  26. Falero-Perez J, Sorenson CM, Sheibani N.Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. Am J Physiol Cell Physiol. 2019 Jun 1;316(6):C767-C781. doi: 10.1152/ajpcell.00021.2019.
  27. Sharick JT, Jeffery JJ, Karim MR, Walsh CM, Esbona K, Cook RS, Skala MC. Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids. Neoplasia. 2019 Jun;21(6):615-626. doi: 10.1016/j.neo.2019.04.004.
  28. Liu TT, Thomas S, McLean DT, Roldán-Alzate A, Hernando D, Ricke EA, Ricke WA (2019). Prostate Enlargement and Altered Urinary Function Are Part of the Aging Process. Aging. 2019 May 13; 11(9):2653-2699. PMID: 31085797; PMC6535061; DOI: 10.18632/aging.101938.
  29. Wan J, Block S, Scribano CM, Thiry R, Esbona K, Audhya A, Weaver BA. Mad1 destabilizes p53 by preventing PML from sequestering MDM2. Nat Commun. 2019 Apr 4;10(1):1540. doi: 10.1038/s41467-019-09471-9. PMID: 30948704
  30. Faralli JA, Filla MS, Peters DM. Effect of αvβ3 Integrin Expression and Activity on Intraocular Pressure. Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1776-1788. doi: 10.1167/iovs.18-26038. PMID:31022732
  31. Ren J, Zhou T, Pilli VSS, Phan N, Wang Q, Gupta K, Liu Z, Sheibani N, Liu B. Circ Res. Novel Paracrine Functions of Smooth Muscle Cells in Supporting Endothelial Regeneration Following Arterial Injury. 2019 Apr 12;124(8):1253-1265. doi: 10.1161/CIRCRESAHA.118.314567.
  32. Falero-Perez J, Larsen MC, Teixeira LBC, Zhang HF, Lindner V, Sorenson CM, Jefcoate CR, Sheibani N. Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis. Trends Dev Biol. 2019;12:1-12.
  33. Mezu-Ndubuisi OJ, Wang Y, Schoephoerster J, Falero-Perez J, Zaitoun IS, Sheibani N, Gong S. Intravitreal Delivery of VEGF-A165-loaded PLGA Microparticles Reduces Retinal Vaso-Obliteration in an In Vivo Mouse Model of Retinopathy of Prematurity. Curr Eye Res. 2019 Mar;44(3):275-286. doi: 10.1080/02713683.2018.1542736.
  34. Kumar M, Salem K, Michel CJ, Jeffery JJ, Yan Y, Fowler AM. 18F-Fluoroestradiol Positron Emission Tomography Imaging of Activating Estrogen Receptor Alpha Mutations in Breast Cancer. J Nucl Med. 2019 Mar 8. pii: jnumed.118.224667. doi: 10.2967/jnumed.118.224667. PMID:  30850489
  35. Spurgeon ME, Uberoi A, McGregor SM, Wei T, Ward-Shaw E, Lambert PF. A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract. MBio. 2019 Mar 5;10(2). pii: e00180-19. doi: 10.1128/mBio.00180-19. PMID: 30837335
  36. Roy M, Buehler DG, Zhang R, Schwalbe ML, Baus RM,  Salamat MS, Lloyd RV, Rosenbaum JN. Expression of Insulinoma-Associated Protein 1 (INSM1) and Orthopedia Homeobox (OTP) in Tumors with Neuroendocrine Differentiation at Rare Sites. Endocr Pathol. 2019 Mar;30(1):35-42. doi: 10.1007/s12022-018-9559-y. PMID: 30523500
  37. Chu YH, Hardin H, Eickhoff, Lloyd RV. In Situ Hybridization Analysis of Long Non-coding RNAs MALAT1 and HOTAIR in Gastroenteropancreatic Neuroendocrine Neoplasms. Endocr Pathol. 2019 Mar;30(1):56-63. doi: 10.1007/s12022-018-9564-1. PMID: 30600442
  38. Vellky JE, Ricke EA, W Huang, Ricke WA. Expression and Localization of DDX3 in Prostate Cancer Progression and Metastasis. Am J Pathol. 2019 Mar 27. pii: S0002-9440(18)30965-9. doi: 10.1016/j.ajpath.2019.02.011. PMID: 30926334
  39. Roy M, Buehler DG, Zhang R, Schwalbe ML, Baus RM, Salamat, MS, Lloyd RV, Rosenbaum JN. Expression of Insulinoma-Associated Protein 1 (INSM1) and Orthopedia Homeobox (OTP) in Tumors with Neuroendocrine Differentiation at Rare Sites. Endocr Pathol. 2019 Mar;30(1):35-42. doi: 10.1007/s12022-018-9559-y. PMID:30523500
  40. Yang RK, Zhao P, Lu C, Luo J, Hu R. Expression pattern of androgen receptor and AR-V7 in androgen deprivation therapy naïve salivary duct carcinomas. Hum Pathol. 2018 Sep 26. pii: S0046-8177(18)30371-X. doi: 10.1016/j.humpath.2018.09.009. PMID: 30267779
  41. Huebner SM1, Helfrich KK2, Saini N2, Blohowiak SE3, Cheng AA1, Kling PJ3, Smith SM1,2. Dietary Iron Fortification Normalizes Fetal Hematology, Hepcidin, and Iron Distribution in a Rat Model of Prenatal Alcohol Exposure. Alcohol Clin Exp Res. 2018 Jun;42(6):1022-1033. doi: 10.1111/acer.13754.
  42. Esbona K, Yi Y, Saha S, Yu M, Van Doorn RR, Conklin MW, Graham DS, Wisinski KB, Ponik SM, Eliceiri KW, Wilke LG, Keely PJ. The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients. Am J Pathol. 2018 Mar;188(3):559-573. doi: 10.1016/j.ajpath.2017.10.025. PMID: 29429545
  43. Connor JP, Esbona K, Matkowskyj KA. AKR1B10 expression by immunohistochemistry in surgical resections and fine needle aspiration cytology material in patients with cystic pancreatic lesions; potential for improved nonoperative diagnosis. Hum Pathol. 2017 Dec; 70:77-83. doi: 10.1016/j.humpath.2017.10.006. Epub 2017 Oct 24. PMID: 29079172
  44. Rush, P. S., Rosenbaum, J. N., Roy, M., Baus, R. M., Bennett, D. D., & Lloyd, R. V. (2017). Insulinoma-associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma). Journal of Cutaneous Pathology. doi:10.1111/cup.13079
  45. Mandal, R., Hardin, H., Baus, R., Rehrauer, W., & Lloyd, R. V. (2017). Analysis of miR-96 and miR-133a Expression in Gastrointestinal Neuroendocrine Neoplasms. Endocrine Pathology, 28(4), 345-350. doi:10.1007/s12022-017-9504-5
  46. Covach A, Patel S, Hardin H, Lloyd RV. Phosphorylated Mechanistic Target of Rapamycin (p-mTOR) and Noncoding RNA Expression in Follicular and H?rthle Cell Thyroid Neoplasm. Endocr Pathol. 2017 Jun 28. doi: 10.1007/s12022-017-9490-7. [Epub ahead of print] PubMed PMID: 28660408.
  47. King SN, Woo JH, Tang S, Thibeault SL. Macrophage Response to Allogeneic Adipose Tissue-Derived Stromal Cells in Hyaluronan-Based Hydrogel in a Porcine Vocal Fold Injury Model. Ann Otol Rhinol Laryngol. 2017 Jun;126(6):463-477. doi: 10.1177/0003489417702923. Epub 2017 Apr 6. PubMed PMID: 28385042.
  48. Matson DR, Xu J, Huffman L, Barroilhet L, Accola M, Rehrauer WM, Weisman P. KRAS and GNAS Co-Mutation in Metastatic Low-Grade Appendiceal Mucinous Neoplasm (LAMN) to the Ovaries: A Practical Role for Next-Generation Sequencing. Am J Case Rep. 2017 May 20;18:558-562. PubMed PMID: 28526814; PubMed Central PMCID: PMC5447665.
  49. Imaizumi M, Li-Jessen NY, Sato Y, Yang DT, Thibeault SL. Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering. Ann Otol Rhinol Laryngol. 2017 Apr;126(4):304-314. doi: 10.1177/0003489417691296. Epub 2017 Feb 12. PubMed PMID: 28290232.
  50. Shen AL, Moran SM, Glover EA, Teixeira LB, Bradfield CA (2017) Retinal pathology in the PPCD1 mouse. PLoS ONE 12(10): e0185094
  51. Pointer KB, Clark PA, Eliceiri KW, Salamat MS, Robertson GA, Kuo JS. Administration of Non-Torsadogenic human Ether-go-go-Related Gene Inhibitors Is Associated with Better Survival for High hERG-Expressing Glioblastoma Patients. Clin Cancer Res. 2017 Jan 1;23(1):73-80. doi: 10.1158/1078-0432.CCR-15-3169. Epub 2016 Sep 15. PubMed PMID: 27635088.
  52. Pointer KB, Clark PA, Schroeder AB, Salamat MS, Eliceiri KW, Kuo JS. Association of collagen architecture with glioblastoma patient survival. J Neurosurg. 2017 Jun;126(6):1812-1821. doi: 10.3171/2016.6.JNS152797. Epub 2016 Sep 2. PubMed PMID: 27588592; PubMed Central PMCID: PMC5386834.
  53. Somnay YR, Yu XM, Lloyd RV, Leverson G, Aburjania Z, Jang S, Jaskula-Sztul R, Chen H. Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosis. Cancer. 2017 Mar 1;123(5):769-782. doi: 10.1002/cncr.30403. Epub 2016 Nov 2. PMID:27861750
  54. Pili R, Liu G, Chintala S, Verheul H, Rehman S, Attwood K, Lodge MA, Wahl R, Martin JI, Miles KM, Paesante S, Adelaiye R, Godoy A, King S, Zwiebel J, Carducci MA. Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial. Br J Cancer. 2017 Mar 28;116(7):874-883. doi: 10.1038/bjc.2017.33. Epub 2017 Feb 21. PubMed PMID: 28222071; PubMed Central PMCID: PMC5379145.
  55. Wilking-Busch MJ, Ndiaye MA, Huang W, Ahmad N. Expression profile of SIRT2 in human melanoma and implications for sirtuin-based chemotherapy. Cell Cycle. 2017 Mar 19;16(6):574-577. doi: 10.1080/15384101.2017.1288323. Epub 2017 Feb 6. PubMed PMID: 28166441; PubMed Central PMCID: PMC5384585.
  56. Blute ML Jr, Damaschke N, Wagner J, Yang B, Gleave M, Fazli L, Shi F, Abel EJ, Downs TM, Huang W, Jarrard DF. Persistence of senescent prostate cancer cells following prolonged neoadjuvant androgen deprivation therapy. PLoS One. 2017 Feb 24;12(2): e0172048. doi: 10.1371/journal.pone.0172048. eCollection 2017. PMID:28234906
  57. Johnson MD, Stone B, Thibodeau BJ, Baschnagel AM, Galoforo S, Fortier LE, Ketelsen B, Ahmed S, Kelley Z, Hana A, Wilson TG, Robertson JM, Jury RP, Wilson GD. The significance of Trk receptors in pancreatic cancer. Tumour Biol. 2017 Feb;39(2):1010428317692256. doi: 10.1177/1010428317692256. PubMed PMID: 28218045.
  58. Jang S, Yu XM, Montemayor-Garcia C, Ahmed K, Weinlander E, Lloyd RV, Dammalapati A, Marshall D, Prudent JR, Chen H. Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes. Oncotarget. 2017 Jan 30. doi: 10.18632/oncotarget.14904. PMID:28160550
  59. Barcus CE, O’Leary KA, Brockman JL, Rugowski DE, Liu Y, Garcia N, Yu M, Keely PJ, Eliceiri KW, Schuler LA. Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells. Breast Cancer Res. 2017 Jan 19;19(1):9. doi: 10.1186/s13058-017-0801-1. PubMed PMID: 28103936; PubMed Central PMCID: PMC5244528.
  60. Swick AD, Stein AP, McCulloch TM, Hartig GK, Ong IM, Sampene E, Prabakaran PJ, Liu CZ, Kimple RJ. Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts. Oral Oncol. 2017 Jan;64:65-72. doi: 10.1016/j.oraloncology.2016.11.017. Epub 2016 Dec 8. PubMed PMID: 28024726; PubMed Central PMCID: PMC5218527.
  61. Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Res. 2016 Mar 22;18(1):35. doi: 10.1186/s13058-016-0695-3.
  62. Gertz, R. J., Nikiforov, Y., Rehrauer, W., Mcdaniel, L., & Lloyd, R. V. (2016). Mutation in BRAF and Other Members of the MAPK Pathway in Papillary Thyroid Carcinoma in the Pediatric Population. Archives of Pathology & Laboratory Medicine, 140(2), 134-139. doi:10.5858/arpa.2014-0612-oa
  63. Xu J, Hardin H, Zhang R, Sundling K, Buehler D, Lloyd RV. Stage-Specific Embryonic Antigen-1 (SSEA-1) Expression in Thyroid Tissues. Endocr Pathol. 2016 Dec;27(4):271-275. PMID:27550342
  64. Drifka CR, Loeffler AG, Mathewson K, Keikhosravi A, Eickhoff JC, Liu Y, Weber SM, Kao WJ, Eliceiri KW Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection. Oncotarget. 2016 Nov 15;7(46):76197-76213. doi:10.18632/oncotarget.12772. PMID:27776346
  65. Drifka CR, Loeffler AG, Mathewson K, Mehta G, Keikhosravi A, Liu Y, Lemancik S, Ricke WA, Weber SM, Kao WJ, Eliceiri KW. Comparison of Picrosirius Red Staining With Second Harmonic Generation Imaging for the Quantification of Clinically Relevant Collagen Fiber Features in Histopathology Samples. J Histochem Cytochem. 2016 Sep;64(9):519-29. doi: 10.1369/0022155416659249. Epub 2016 Jul 22. PMID:27449741
  66. Bauman TM, Vezina CM, Ricke EA, Halberg RB, Huang W, Peterson R, Ricke WA. Expression and colocalization of β-catenin and lymphoid enhancing factor-1 in prostate cancer progression. Hum Pathol. 2016 May; 51:124-33. doi: 10.1016/j.humpath.2015.12.024. Epub 2016 Jan 19.
  67. Bauman TM, Ricke EA, Drew SA, Huang W, Ricke WA. Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging. J Vis Exp. 2016 Apr 8;(110). doi: 10.3791/53837.
  68. George J, Nihal M, Singh CK, Zhong W, Liu X, Ahmad N. Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma. J Invest Dermatol. 2016Apr;136(4):809-18. doi: 10.1016/j.jid.2015.12.026.
  69. Denu, R. A., Zasadil, L. M., Kanugh, C., Laffin, J., Weaver, B. A., Burkard, M. E. Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer. BMC Cancer201616:47 DOI: 10.1186/s12885-016-2083-x (2016).
  70. Yu W, Denu RA, Krautkramer KA, Grindle KM, Yang DT, Asimakopoulos F, Hematti P, Denu JM. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies. J Biol Chem. 2016 Feb 12;291(7):3268-79. doi: 10.1074/jbc.M115.702076. PMID:26631723
  71. Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin JJ, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer. Mol Cancer Ther. 2016;15(1):48-59. Epub 2015/11/21. doi: 10.1158/1535-7163.mct-15-0527. PubMed PMID: 26586723; PMCID: PMC4707107.
  72. Denu RA, Zasadil LM, Kanugh C, Laffin J, Weaver BA, Burkard ME. Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer. BMC Cancer. 2016; 16:47. Epub 2016/02/03. doi: 10.1186/s12885-016-2083-x. PubMed PMID: 26832928; PMCID: PMC4734858.
  73. Francis DM, Huang S, Armstrong EA, Werner LR, Hullett C, Li C, Morris ZS, Swick AD, Kragh M, Lantto J, Kimple RJ, Harari PM. Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models. Clin Cancer Res. 2016;22(3):633-43. Epub 2015/10/01. doi: 10.1158/1078-0432.ccr-15-1664. PubMed PMID: 26420857.
  74. Gee JR, Saltzstein DR, Messing E, Kim K, Kolesar J, Huang W, Havighurst TC, Harris L, Wollmer BW, Jarrard D, House M, Parnes H, Bailey HH. Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy. Eur J Cancer Prev. 2016;25(4):312-20. Epub 2015/08/28. doi: 10.1097/cej.0000000000000189. PubMed PMID: 26313229.
  75. Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran PJ, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab. Mol Cancer Ther. 2016;15(9):2175-86. Epub 2016/07/17. doi: 10.1158/1535-7163.mct-16-0012. PubMed PMID: 27422810; PMCID: PMC5010956.
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